Active Recombinant Mouse Interleukin 17A, MIgG2a Fc-tagged
Cat.No. : | IL17A-001H |
Product Overview : | The extracellular domain of mouse IL-17 (NP_034682.1)(Met1-Leu142) is fused to the N-terminus of the Fc region of a mouse IgG2a was expressed in CHO cell. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokineregulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate theexpression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoidarthritis, psoriasis and multiple sclerosis. |
Source : | CHO cell |
Species : | Mouse |
Tag : | MIgG2a Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to induce IL-6 secretion . |
Molecular Mass : | 39KDa (monomer) |
AA Sequence : | Met1-Leu142 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | Il17a interleukin 17A [ Mus musculus ] |
Official Symbol : | IL17A |
Synonyms : | IL17A; interleukin 17A; interleukin-17A; cytotoxic T-lymphocyte-associated antigen 8; Il17; Ctla8; IL-17; Ctla-8; IL-17A; |
Gene ID : | 16171 |
mRNA Refseq : | NM_010552 |
Protein Refseq : | NP_034682 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Rheumatoid arthritis, organism-specific biosystem; Rheumatoid arthritis, conserved biosystem; |
Function : | cytokine activity; |
Products Types
◆ Lysates | ||
IL17A-001HCL | Recombinant Human IL17A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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