"IL18" Related Products

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Recombinant Human IL18, HIgG1 Fc-tagged

Cat.No.: IL18-551H
Product Overview: The extracellular domain of human IL-18 (NP_001553.1)(Tyr37-Asp193) is fused to the N-terminus of the Fc region of a human IgG1 was expressed in CHO cell.
Description: The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity inspleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively splicedtranscript variants encoding different isoforms have been found for this gene
Source: CHO cell
Species: Human
Tag: HIgG1 Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Induction of IFN-γ in response to the recombinant human IL-18 was measured using human IFN-γ ELISA.
Molecular Mass: 44KDa (monomer)
AA Sequence: Tyr37-Asp193
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: IL18 interleukin 18 (interferon-gamma-inducing factor) [ Homo sapiens ]
Official Symbol: IL18
Synonyms: IL18; interleukin 18 (interferon-gamma-inducing factor); interleukin-18; IGIF; IL 1g; IL 18; IL1F4; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; IL-18; IL-1g; MGC12320;
Gene ID: 3606
mRNA Refseq: NM_001243211
Protein Refseq: NP_001230140
MIM: 600953
UniProt ID: Q14116
Chromosome Location: 11q22.2-q22.3
Pathway: African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cellular roles of Anthrax toxin, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem;
Function: cytokine activity; cytokine activity;

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