"FLT3LG" Related Products

Recombinant Human Fms-related Tyrosine Kinase 3 Ligand, HIgG1 Fc-tagged

Cat.No.: FLT3LG-278H
Product Overview: The extracellular domain of human FLT3L (AAI26294.1) (Thr27-Pro184) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell
Description: Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens andpriming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly importantfor plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positivetissue counterparts
Source: CHO cell
Species: Human
Tag: HIgG1 Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured in a cell proliferation assay.
Molecular Mass: 44KDa (monomer)
AA Sequence: Thr27-Pro184
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: FLT3LG fms-related tyrosine kinase 3 ligand [ Homo sapiens ]
Official Symbol: FLT3LG
Synonyms: FLT3LG; fms-related tyrosine kinase 3 ligand; flt3 ligand; FL; FLT3L;
Gene ID: 2323
mRNA Refseq: NM_001204502
Protein Refseq: NP_001191431
MIM: 600007
UniProt ID: P49771
Chromosome Location: 19q13.3
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Pathways in cancer, organism-specific biosystem;
Function: cytokine activity; protein homodimerization activity; receptor binding; receptor tyrosine kinase binding;

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