Active Recombinant Human VSIG4, HIgG1 Fc-tagged
Cat.No. : | VSIG4-511H |
Product Overview : | The extracellular domain of human VSIG4(AAH10525.1) (Arg20-Pro283) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. |
Source : | CHO cell |
Species : | Human |
Tag : | HIgG1 Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its binding ability in a functional ELISA. |
AA Sequence : | Arg20-Pro283 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | VSIG4 V-set and immunoglobulin domain containing 4 [ Homo sapiens ] |
Official Symbol : | VSIG4 |
Synonyms : | VSIG4; V-set and immunoglobulin domain containing 4; V-set and immunoglobulin domain-containing protein 4; Z39IG; protein Z39Ig; Ig superfamily protein; complement receptor of the immunoglobulin superfamily; CRIg; |
Gene ID : | 11326 |
mRNA Refseq : | NM_001100431 |
Protein Refseq : | NP_001093901 |
MIM : | 300353 |
UniProt ID : | Q9Y279 |
Chromosome Location : | Xq12-q13.3 |
Function : | protein binding; |
Products Types
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VSIG4-490H | Recombinant Human VSIG4 Protein, MYC/DDK-tagged | +Inquiry |
Vsig4-122M | Recombinant Mouse Vsig4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Vsig4-6948M | Recombinant Mouse Vsig4 Protein, Myc/DDK-tagged | +Inquiry |
Vsig4-861M | Active Recombinant Mouse Vsig4 Protein, Fc Chimera | +Inquiry |
◆ Lysates | ||
VSIG4-2519MCL | Recombinant Mouse VSIG4 cell lysate | +Inquiry |
VSIG4-1092HCL | Recombinant Human VSIG4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionVSIG4 has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.
There are no drugs that directly regulate VSIG4 levels, but they can affect VSIG4 expression and function by modulating the immune system.
Mutations in VSIG4 can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.
VSIG4 plays an important role in tumor immunity, which can inhibit the activation and function of T cells and NK cells, thereby promoting tumor growth and metastasis.
Studying the regulatory mechanism of VSIG4 requires a combination of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.
The types of mutations in VSIG4 include point mutations, insertions/deletions, duplications, etc., which can cause structural and functional abnormalities of the protein.
Customer Reviews (3)
Write a reviewStable performance, excellent performance in a variety of experiments.
No side effects, high safety.
It has good antigenicity and can induce target immune response.
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