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Recombinant Human SEMA5A, HIgG1 Fc-tagged

Cat.No.: SMA5A-3512H
Product Overview: The extracellular domain of human SEMA5A (AAI15697.1) (Glu23-Thr765) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell
Description: This gene belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain andseveral thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neuraldevelopment. This gene has been implicated as an autism susceptibility gene
Source: CHO cell
Species: Human
Tag: HIgG1 Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by its ability to inhibit proliferation.
Molecular Mass: 110KDa (monomer)
AA Sequence: Glu23-Thr765
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A [ Homo sapiens ]
Official Symbol: SEMA5A
Synonyms: SEMA5A; sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A; SEMAF; semaphorin-5A; semF; sema F; semaphorin F; semaphorin-F; FLJ12815;
Gene ID: 9037
mRNA Refseq: NM_003966
Protein Refseq: NP_003957
MIM: 609297
UniProt ID: Q13591
Chromosome Location: 5p15.2
Pathway: Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Other semaphorin interactions, organism-specific biosystem; Semaphorin interactions, organism-specific biosystem;
Function: axon guidance receptor activity; receptor activity;

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