Active Recombinant Human VTCN1, HIgG1 Fc-tagged
Cat.No. : | VTCN1-530H |
Product Overview : | The extracellular domain of human B7-H4(NP_078902.2)(Phe29-Ala258) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell |
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- Gene Information
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Description : | This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene |
Source : | CHO cells |
Species : | Human |
Tag : | HIgG1 Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by the ablility to inhibit anti-CD3-induced proliferation of stimulated human T cells. Human T lymphocytes cultured for 72 hours with PHA were incubated for an additional 3 days in 96 well place coated with 500 ng/ml anti-CD3 and 10 ug/ml human B |
Molecular Mass : | 55 KDa (monomer) |
AA Sequence : | Phe29-Ala258 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | VTCN1 V-set domain containing T cell activation inhibitor 1 [ Homo sapiens ] |
Official Symbol : | VTCN1 |
Synonyms : | VTCN1; V-set domain containing T cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; B7 family member; H4; B7 superfamily member 1; B7 H4; B7H4; B7S1; B7X; FLJ22418; B7 family member, H4; T cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; immune costimulatory protein B7-H4; B7-H4; B7h.5; VCTN1; PRO1291; RP11-229A19.4; |
Gene ID : | 79679 |
mRNA Refseq : | NM_001253849 |
Protein Refseq : | NP_001240778 |
MIM : | 608162 |
UniProt ID : | Q7Z7D3 |
Chromosome Location : | 1p12 |
Function : | receptor binding; |
Products Types
◆ Recombinant Protein | ||
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VTCN1-604H | Recombinant Human VTCN1 Protein | +Inquiry |
Vtcn1-152M | Recombinant Mouse Vtcn1 Protein, His (Fc)-Avi-tagged | +Inquiry |
VTCN1-4295H | Recombinant Human VTCN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
VTCN1-787M | Recombinant Mouse VTCN1 Protein (Phe29-Ser256), His-tagged | +Inquiry |
◆ Lysates | ||
VTCN1-1636MCL | Recombinant Mouse VTCN1 cell lysate | +Inquiry |
VTCN1-1096HCL | Recombinant Human VTCN1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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