"CCL4" Related Products

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Recombinant Human Chemokine (C-C Motif) Ligand 4, MIgG2a Fc-tagged

Cat.No.: CCL4-119H
Product Overview: The extracellular domain of human CCL4 (AAI04227.1) (Ala24-Asn92) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO celL
Description: The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions.
Source: CHO cells
Species: Human
Tag: MIgG2a Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR5.
Molecular Mass: 34 KDa (monomer)
AA Sequence: Ala24-Asn92
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: CCL4 chemokine (C-C motif) ligand 4 [ Homo sapiens ]
Official Symbol: CCL4
Synonyms: CCL4; chemokine (C-C motif) ligand 4; LAG1, SCYA4, small inducible cytokine A4 (homologous to mouse Mip 1b); C-C motif chemokine 4; Act 2; AT744.1; MIP 1 beta; PAT 744; SIS-gamma; MIP-1-beta(1-69); CC chemokine ligand 4; secreted protein G-26; T-cell activation protein 2; small-inducible cytokine A4; lymphocyte-activation gene 1; G-26 T-lymphocyte-secreted protein; lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; small inducible cytokine A4 (homologous to mouse Mip-1b); ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; MIP-1-beta; MGC104418; MGC126025; MGC126026;
Gene ID: 6351
mRNA Refseq: NM_002984
Protein Refseq: NP_002975
MIM: 182284
UniProt ID: P13236
Chromosome Location: 17q21-q23
Pathway: Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem;
Function: CCR1 chemokine receptor binding; CCR5 chemokine receptor binding; chemokine activity; cytokine activity;

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