Active Recombinant Human DcR3, HIgG1 Fc-tagged
Cat.No. : | DcR3-678H |
Product Overview : | A soluble dimeric fusion protein consisting of the extracellular domain of human DcR3(O95407) (Val24-His300) was fused to human IgG1 Fc. |
- Specification
- Gene Information
- Related Products
Description : | This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript |
Source : | CHO cell |
Species : | Human |
Tag : | HIgG1 Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
AA Sequence : | A soluble dimeric fusion protein consisting of the extracellular domain of human DcR3(O95407) (Val24-His300) was fused to human IgG1 Fc. |
Endotoxin : | <0.06eu mu;g as determined by lal>0.06eu> |
Purity : | >98%(SDS-PAGE) |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy [ Homo sapiens (human) ] |
Official Symbol : | DcR3 |
Synonyms : | TNFRSF6B; M68; TR6; DCR3; M68E; DJ583P15.1.1; tumor necrosis factor receptor superfamily, member 6b, decoy; tumor necrosis factor receptor superfamily member 6B; decoy receptor 3; decoy receptor for Fas ligand |
Gene ID : | 8771 |
mRNA Refseq : | NM_003823 |
Protein Refseq : | NP_003814 |
MIM : | 603361 |
UniProt ID : | O95407 |
Chromosome Location : | 20q13.3 |
Pathway : | Apoptosis Modulation and Signaling; Cytokine-cytokine receptor interaction; Cytosolic Iron-sulfur Cluster Assembly |
Function : | protein binding; receptor activity |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All DcR3 Products
Required fields are marked with *
My Review for All DcR3 Products
Required fields are marked with *
0
Inquiry Basket