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Active Recombinant Human DcR3, HIgG1 Fc-tagged

Cat.No. : DcR3-678H
Product Overview : A soluble dimeric fusion protein consisting of the extracellular domain of human DcR3(O95407) (Val24-His300) was fused to human IgG1 Fc.
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  • Gene Information
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Description : This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript
Source : CHO cell
Species : Human
Tag : HIgG1 Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
AA Sequence : A soluble dimeric fusion protein consisting of the extracellular domain of human DcR3(O95407) (Val24-His300) was fused to human IgG1 Fc.
Endotoxin : <0.06eu mu;g as determined by lal>
Purity : >98%(SDS-PAGE)
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy [ Homo sapiens (human) ]
Official Symbol : DcR3
Synonyms : TNFRSF6B; M68; TR6; DCR3; M68E; DJ583P15.1.1; tumor necrosis factor receptor superfamily, member 6b, decoy; tumor necrosis factor receptor superfamily member 6B; decoy receptor 3; decoy receptor for Fas ligand
Gene ID : 8771
mRNA Refseq : NM_003823
Protein Refseq : NP_003814
MIM : 603361
UniProt ID : O95407
Chromosome Location : 20q13.3
Pathway : Apoptosis Modulation and Signaling; Cytokine-cytokine receptor interaction; Cytosolic Iron-sulfur Cluster Assembly
Function : protein binding; receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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