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Active Recombinant Human IL22, HIgG1 Fc-tagged, mutant

Cat.No. : IL22-562H
Product Overview : The extracellular domain of human IL-22 (NP_065386.1) (Ala34-ILe179) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell.
  • Specification
  • Gene Information
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Description : L22 (interleukin 22) is a protein-coding gene. Diseases associated with IL22 include?chronic mucocutaneous candidiasis, and?candidiasis, and among its?related super-pathways?are?MIF Mediated Glucocorticoid Regulation?and?Regulation of eIF4 and p70S6K. GO annotations related to this gene include?cytokine activity?and?interleukin-22 receptor binding.
Source : CHO cells
Species : Human
Tag : HIgG1 Fc-tagged, mutant
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : The Biological Activity was determined by the ability to activiate STAT following receptor ligand interaction.
Molecular Mass : 46 KDa (monomer)
AA Sequence : Ala34-ILe179
Endotoxin : <0.06 eu/μg as determined by lal>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : IL22 interleukin 22 [ Homo sapiens ]
Official Symbol : IL22
Synonyms : IL22; interleukin 22; interleukin-22; IL 10 related T cell derived inducible factor; IL 21; IL 22; IL D110; IL TIF; ILTIF; MGC79382; MGC79384; TIFa; TIFIL 23; zcyto18; cytokine Zcyto18; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL-22; IL-TIF; IL-D110; TIFIL-23;
Gene ID : 50616
mRNA Refseq : NM_020525
Protein Refseq : NP_065386
MIM : 605330
UniProt ID : Q9GZX6
Chromosome Location : 12q15
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function : cytokine activity; interleukin-22 receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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