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Recombinant Human CD83, HIgG1 Fc-tagged

Cat.No.: CD83-1065H
Product Overview: The extracellular domain of human CD83 (NP_004224.1) (Thr20-Ala131) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell
Description: The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene
Source: CHO cells
Species: Human
Tag: HIgG1 Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of human monocyte-derived dendritic cells.
Molecular Mass: 41 KDa (monomer)
AA Sequence: Thr20-Ala131
Endotoxin: <0.06 eu/μg as determined by lal>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: CD83 CD83 molecule [ Homo sapiens ]
Official Symbol: CD83
Synonyms: CD83; CD83 molecule; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily) , CD83 molecule; CD83 antigen; BL11; HB15; hCD83; B-cell activation protein; cell surface protein HB15; cell-surface glycoprotein; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily);
Gene ID: 9308
mRNA Refseq: NM_001040280
Protein Refseq: NP_001035370
MIM: 604534
UniProt ID: Q01151
Chromosome Location: 6p23

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