Recombinant Human OLIG2, GST-tagged
Cat.No. : | OLIG2-38H |
Product Overview : | Recombinant Human OLIG2 was expressed as gst-tagged fusion protein by E.Coli and puri?ed by GSH-sepharose. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Storage : | The protein is stored in PBS bu?er at -20 oC. Reepeated freeze-thaw cycles should be avoided. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | OLIG2 oligodendrocyte lineage transcription factor 2 [ Homo sapiens ] |
Official Symbol : | OLIG2 |
Synonyms : | OLIG2; oligodendrocyte lineage transcription factor 2; oligodendrocyte transcription factor 2; protein kinase C-binding protein 2; class B basic helix-loop-helix protein 1; class E basic helix-loop-helix protein 19; human protein kinase C-binding protein RACK17; basic domain, helix-loop-helix protein, class B, 1; oligodendrocyte-specific bHLH transcription factor 2; BHLHB1; OLIGO2; RACK17; PRKCBP2; bHLHe19 |
Gene ID : | 10215 |
mRNA Refseq : | NM_005806 |
Protein Refseq : | NP_005797 |
MIM : | 606386 |
UniProt ID : | Q13516 |
Chromosome Location : | 21q22.11 |
Pathway : | Neural Crest Differentiation |
Function : | DNA binding; HMG box domain binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; protein homodimerization activity |
Products Types
◆ Recombinant Protein | ||
Olig2-4590M | Recombinant Mouse Olig2 Protein, Myc/DDK-tagged | +Inquiry |
OLIG2-1578H | Recombinant Human OLIG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
OLIG2-4438H | Recombinant Human OLIG2 protein, His-SUMO-tagged | +Inquiry |
OLIG2-9574Z | Recombinant Zebrafish OLIG2 | +Inquiry |
OLIG2-28318TH | Active Recombinant Human OLIG2, GST-tagged | +Inquiry |
◆ Lysates | ||
OLIG2-1248HCL | Recombinant Human OLIG2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionOLIG2 is essential for the development and maturation of oligodendrocytes, which form myelin in the nervous system.
OLIG2 is implicated in the development of gliomas, influencing tumor cell differentiation and growth.
OLIG2 plays a crucial role in directing neural stem cells to differentiate into oligodendrocytes and neurons in the CNS.
OLIG2 affects interactions between neurons and glial cells, essential for proper brain development.
Changes in OLIG2 can lead to neurodevelopmental disorders due to altered brain cell development and function.
OLIG2 contributes to myelin repair and regeneration, crucial in demyelinating diseases like multiple sclerosis.
OLIG2 modulates gene expression, guiding key neurodevelopmental processes and cell fate decisions.
Customer Reviews (3)
Write a reviewSwift protein sequencing, invaluable for protein identification.
Consistent western blot results, a lab necessity for us.
Great protein crystallization service, vital for structural biology studies.
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