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Recombinant Human Placental Growth Factor

Cat.No. : PGF-97H
Product Overview : Recombinant Human Placenta Growth Factor-1 produced in insect cells is a homodimer, glycosylated polypeptide chain containing 2 x 131 amino acids and having a total molecular mass of 29.7 kDa. The PLGF-1 is purified by proprietary chromatographic techniques.
  • Specification
  • Gene Information
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Cat. No. : PGF-97H
Description : PLGF is a growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration. It binds to receptor vegfr-1/flt1.
Source : Insect Cells
Physical Appearance : Sterile Filtered White lyophilized (freeze-dried) powder.
Purity : Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation : Lyophilized from a concentrated (1 mg/ml) solution containing BSA.
Solubility : It is recommended to reconstitute the lyophilized Placenta Growth Factor 1 in sterile 20 mM acetic acid not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Specific Activity : The ED50as determined by its ability to bind to immobilized rh-sFlt-1 in a functional ELISA. PlGF-1 human Recombinant can bind to immobilized rh-sFlt-1 (100 ng/well) with a linear range at 0.5 – 10 ng/mL.
Stability : Lyophilized Placenta Growth Factor 1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PLGF1 should be stored at 4°Cbetween 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
Gene Name : PGF placental growth factor [ Homo sapiens ]
Synonyms : PGF; placental growth factor; PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760; placental growth factor, vascular endothelial growth factor-related protein; placental growth factor-like; PlGF; factor-related protein
Gene ID : 5228
mRNA Refseq : NM_002632
Protein Refseq : NP_002623
MIM : 601121
UniProt ID : P49763
Chromosome Location : 14q24-q31
Pathway : Bladder cancer; Cytokine-cytokine receptor interaction; Focal adhesion; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; mTOR signaling pathway
Function : growth factor activity; heparin binding; protein binding; protein heterodimerization activity; protein homodimerization activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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