"RFXAP" Related Products

Recombinant Human RFXAP cell lysate

Cat.No.: RFXAP-1496HCL
Description: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: RFXAP regulatory factor X-associated protein [ Homo sapiens ]
Official Symbol: RFXAP
Synonyms: RFXAP; regulatory factor X-associated protein; RFX-associated protein; RFX DNA-binding complex 36 kDa subunit;
Gene ID: 5994
mRNA Refseq: NM_000538
Protein Refseq: NP_000529
MIM: 601861
UniProt ID: O00287
Chromosome Location: 13q14
Pathway: Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Primary immunodeficiency, organism-specific biosystem; Primary immunodeficiency, conserved biosystem; Tuberculosis, organism-specific biosystem; Tuberculosis, conserved biosystem;
Function: DNA binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity;

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