Recombinant Human RGS1 cell lysate

• Cat.No.: RGS1-1499HCL

Specification

• Description: This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: RGS1 regulator of G-protein signaling 1 [ Homo sapiens ]
• Official Symbol: RGS1
• Synonyms: RGS1; regulator of G-protein signaling 1; IER1, regulator of G protein signalling 1; 1R20; BL34; IR20; early response protein 1R20; B-cell activation protein BL34; regulator of G-protein signalling 1; immediate-early response 1, B-cell specific; IER1
• Gene ID: 5996
• mRNA Refseq: NM_002922
• Protein Refseq: NP_002913
• MIM: 600323
• UniProt ID: Q08116
• Chromosome Location: 1q31
• Pathway: CXCR4-mediated signaling events, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem
• Function: GTPase activator activity; calmodulin binding