"MYC" Related Products

Expand
Expand
Expand

Recombinant Human MYC, His-tagged

Cat.No.: MYC-38H
Product Overview: Recombinant Human MYC (Pro2-Ala439), fused with N-terminal 6x histidine tag, was expressed in E.coli.
Description: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Source: E.coli
Species: Human
Tag: His
Form: Lyophilized powder. Lyophilized from a 0.2 µm filtered solution in PBS.
Molecular Mass: 51 kDa
Endotoxin: Not determined
Purity: >85%
Applications: ELISA, EIA, Western Blotting, Dot Blotting, Immunoprecipitation, Protein Array, Functional Assay, etc.
Storage: Upon arrival, the lyophilized protein may be stored for 2 weeks at 4°C. For long term storage, it is recommended to store desiccated below -20°C in a manual defrost freezer. Following reconstitution, the protein may be stored for 2 weeks under sterile conditions at -20°C. For long term storage, it is recommended to make appropriate aliquots and store at -80°C. Avoid repeated freeze-thaw cycles.
Preservative: None
Reconstitution: Briefly spin the vial and bring the contents to the bottom prior to opening. It is recommended to reconstitute at 0.5~1.17 mg/mL with sterile deionized water.
Shipping: Upon arrival, the lyophilized products may be stored for 2 weeks at 4 °C. For long term storage, it is recommended to be stored desiccated below -20 °C in a manual defrost freezer. Following reconstitution, the protein may be stored for 2 weeks under sterile conditions at 4 °C. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA) and store at -20 °C or -80 °C in appropriate aliquots. Avoid repeated freeze-thaw cycles.
Gene Name: MYC v-myc myelocytomatosis viral oncogene homolog (avian) [ Homo sapiens ]
Official Symbol: MYC
Synonyms: MYC; MRTL; c-Myc; bHLHe39; myc proto-oncogene protein; OTTHUMP00000158589; OTTHUMP0000022- 7763; proto-oncogene c-Myc; transcription factor p64; class E basic helix-loop-helix protein 39; avian myelo- cytomatosis viral oncogene homolog; v-myc avian myelocytomatosis viral oncogene homolog; myc-related translation/localization regulatory factor; Proto-oncoge- ne c-Myc; Transcription factor p64; Class E basic helix-loop-helix protein 39
Gene ID: 4609
mRNA Refseq: NM_002467
Protein Refseq: NP_002458
MIM: 190080
UniProt ID: P01106
Chromosome Location: 8q24.21
Pathway: Acute myeloid leukemia; C-MYC pathway; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Function: DNA binding; E-box binding; protein binding; sequence-specific DNA binding transcription factor activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.