| Description : |
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. |
| Source : |
E.coli |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized powder. Lyophilized from a 0.2 µm filtered solution in PBS. |
| Molecular Mass : |
51 kDa |
| Endotoxin : |
Not determined |
| Purity : |
>85% |
| Applications : |
ELISA, EIA, Western Blotting, Dot Blotting, Immunoprecipitation, Protein Array, Functional Assay, etc. |
| Storage : |
Upon arrival, the lyophilized protein may be stored for 2 weeks at 4°C. For long term storage, it is recommended to store desiccated below -20°C in a manual defrost freezer. Following reconstitution, the protein may be stored for 2 weeks under sterile conditions at -20°C. For long term storage, it is recommended to make appropriate aliquots and store at -80°C. Avoid repeated freeze-thaw cycles. |
| Preservative : |
None |
| Reconstitution : |
Briefly spin the vial and bring the contents to the bottom prior to opening. It is recommended to reconstitute at 0.5~1.17 mg/mL with sterile deionized water. |
| Shipping : |
Upon arrival, the lyophilized products may be stored for 2 weeks at 4 °C. For long term storage, it is recommended to be stored desiccated below -20 °C in a manual defrost freezer. Following reconstitution, the protein may be stored for 2 weeks under sterile conditions at 4 °C. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA) and store at -20 °C or -80 °C in appropriate aliquots. Avoid repeated freeze-thaw cycles. |
