Recombinant Human PLA2G1B protein, His-tagged
Cat.No. : | PLA2G1B-171H |
Product Overview : | Recombinant Human PLA2G1B (Ala23-Ser148) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
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Description : | Phosphatidylcholine 2-acylhydrolase 1B (PLA2G1B) is also known as Phospholipase A2 (PLA2), PLA2A, PPLA2, which belongs to the phospholipase A2 family. PLA2G1B is activated by trypsin cleavage in the duodenum and can also be activated by thrombin or autocatalytically. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Ala23 |
Form : | Lyophilized from 0.22 μm filtered solution in 20 mM Hepes, 150 mM NaCl, pH7.0, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 15.0 kDa. The protein migrates as 19 kDa under reducing (R) condition (SDS-PAGE). |
Protein length : | Ala23-Ser148 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | PLA2G1B |
Official Symbol : | PLA2G1B |
Synonyms : | PLA2G1B; phospholipase A2, group IB (pancreas); PLA2, PLA2A, PPLA2; phospholipase A2; group IB phospholipase A2; phosphatidylcholine 2-acylhydrolase 1B; PLA2; PLA2A; PPLA2; MGC119834; MGC119835 |
Gene ID : | 5319 |
mRNA Refseq : | NM_000928 |
Protein Refseq : | NP_000919 |
MIM : | 172410 |
UniProt ID : | P04054 |
Products Types
◆ Recombinant Protein | ||
PLA2G1B-4147R | Recombinant Rat PLA2G1B Protein, His (Fc)-Avi-tagged | +Inquiry |
PLA2G1B-3867H | Recombinant Human PLA2G1B Protein, His (Fc)-Avi-tagged | +Inquiry |
PLA2G1B-1878H | Recombinant Human PLA2G1B Protein, MYC/DDK-tagged | +Inquiry |
Pla2g1b-4898M | Recombinant Mouse Pla2g1b Protein, Myc/DDK-tagged | +Inquiry |
PLA2G1B-832H | Recombinant Human PLA2G1B Protein | +Inquiry |
◆ Lysates | ||
PLA2G1B-2033MCL | Recombinant Mouse PLA2G1B cell lysate | +Inquiry |
PLA2G1B-2200HCL | Recombinant Human PLA2G1B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionPLA2G1B is associated with atherosclerosis and other cardiovascular conditions due to its involvement in lipid metabolism and inflammation.
Modulating PLA2G1B activity could be explored for potential neuroprotective effects, given its involvement in processes related to neuroinflammation.
Dysregulation of PLA2G1B has been linked to inflammatory disorders, cardiovascular diseases, and certain cancers.
Yes, targeting PLA2G1B may be a potential therapeutic strategy for inflammatory diseases, as it plays a role in the production of inflammatory mediators.
Inhibiting PLA2G1B may be explored as a therapeutic approach in cancer treatment by disrupting lipid metabolism and inhibiting cancer cell proliferation.
Customer Reviews (3)
Write a reviewIts exceptional purity and stability make it an ideal choice for a wide range of applications, ensuring reliable and reproducible results.
The PLA2G1B protein comes highly recommended for its exceptional performance in various research applications.
Its unique characteristics contribute to obtaining clear and detailed structural information, allowing researchers to gain insights into protein interactions and conformational changes.
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