Recombinant Human FCER1A, His-tagged
Cat.No. : | FCER1A-204H |
Product Overview : | Recombinant Human FCER1A, fused with a polyhistidine tag at the C-terminus, was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Molecular Mass : | Biotinylated rh FCER1A is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 21.9 kDa. The predicted N-terminus is Val 26. DTT-reduced Protein migrates as 40-60 kDa in SDS-PAGE due to glycosylation. |
Endotoxin : | Less than 1.0 EU per μg of the Biotinylated rh FCER1A by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Reconstitution : | See Certificate of Analysis for reconstitution instructions and specific concentrations. |
Gene Name : | FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide [ Homo sapiens (human) ] |
Official Symbol : | FCER1A |
Synonyms : | FCER1A; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; FCE1A; high affinity immunoglobulin epsilon receptor subunit alpha; Fc-epsilon RI-alpha; Fc epsilon RI alpha-chain; igE Fc receptor subunit alpha; Fc IgE receptor, alpha polypeptide; high affinity immunoglobulin epsilon receptor alpha-subunit; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; FcERI |
Gene ID : | 2205 |
mRNA Refseq : | NM_002001 |
Protein Refseq : | NP_001992 |
MIM : | 147140 |
UniProt ID : | P12319 |
Chromosome Location : | 1q23 |
Pathway : | Asthma; Fc epsilon RI signaling pathway; Fc epsilon receptor (FCERI) signaling; Immune System |
Function : | IgE binding; IgE receptor activity |
Products Types
◆ Recombinant Protein | ||
FCER1A-1961R | Recombinant Rat FCER1A Protein, His (Fc)-Avi-tagged | +Inquiry |
Fcer1a-8688M | Recombinant Mouse Fcer1a protein(Met1-Gln204), hFc-tagged | +Inquiry |
FCER1A-2929H | Recombinant Human FCER1A Protein, His (Fc)-Avi-tagged | +Inquiry |
FCER1A-338H | Recombinant Human FCER1A Protein(Val26-Gln205), His-tagged | +Inquiry |
FCER1A-25H | Active Recombinant Human FCER1A Protein (26-205aa), C-His tagged | +Inquiry |
◆ Lysates | ||
FCER1A-1389MCL | Recombinant Mouse FCER1A cell lysate | +Inquiry |
FCER1A-1394HCL | Recombinant Human FCER1A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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