Recombinant Human PHLPP2, GST-tagged
Cat.No. : | PHLPP2-1615H |
Product Overview : | Recombinant human PHLPP2 (766-1043) was expressed in E. coli cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | PHLPP2 or PH domain and leucine rich repeat protein phosphatase 2 is the important regulators of Akt serine-threonine kinases and conventional/novel protein kinase C (PKC) isoforms. PHLPP1 and PHLPP2 differentially regulated AKT signaling by selectively dephosphorylating the hydrophobic motifs of AKT2 or AKT3. PHLPP may act as a tumor suppressor in several types of cancer due to its ability to block growth factor-induced signaling in cancer cells. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~ 56 kDa |
Protein length : | 766-1043 |
Purity : | >95% |
Applications : | Phosphatase Assay; Western Blot |
Stability : | 1 yr at -70oC from date of shipment. |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 ug/ul |
Gene Name : | PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 [ Homo sapiens ] |
Official Symbol : | PHLPP2 |
Synonyms : | PHLPP2; PH domain and leucine rich repeat protein phosphatase 2; PH domain and leucine rich repeat protein phosphatase like , PHLPPL; PH domain leucine-rich repeat-containing protein phosphatase 2; KIAA0931; PHLPPL |
Gene ID : | 23035 |
mRNA Refseq : | NM_015020 |
Protein Refseq : | NP_055835 |
MIM : | 611066 |
UniProt ID : | Q6ZVD8 |
Chromosome Location : | 16q22.2 |
Pathway : | Adaptive Immune System; DAP12 signaling; Downstream signaling events of B Cell Receptor (BCR); Downstream signaling of activated FGFR |
Function : | metal ion binding; protein serine/threonine phosphatase activity |
Products Types
◆ Recombinant Protein | ||
PHLPP2-1670H | Recombinant Human PHLPP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Phlpp2-4843M | Recombinant Mouse Phlpp2 Protein, Myc/DDK-tagged | +Inquiry |
PHLPP2-5880Z | Recombinant Zebrafish PHLPP2 | +Inquiry |
PHLPP2-1690H | Recombinant Human PHLPP2, His-tagged | +Inquiry |
PHLPP2-1615 | Recombinant Human PHLPP2 protein, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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