Recombinant Human PCNA, His-tagged
Cat.No. : | PCNA-4863H |
Product Overview : | Recombinant full-length human PCNA was expressed by E. coli cells using an N-terminal His tag. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.? |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~37 kDa |
Protein length : | Full Length |
Purity : | >90% |
Applications : | Western Blot |
Stability : | 1 yr at -70oC from date of shipment. |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.2 ug/ul |
Gene Name : | PCNA proliferating cell nuclear antigen [ Homo sapiens ] |
Official Symbol : | PCNA |
Synonyms : | MGC8367; PCNA;?Proliferating cell nuclear antigen; Cyclin;?proliferating cell nuclear antigen; cyclin; DNA polymerase delta auxiliary protein |
Gene ID : | 5111 |
mRNA Refseq : | NM_002592 |
Protein Refseq : | NP_002583 |
MIM : | 176740 |
UniProt ID : | P12004 |
Chromosome Location : | 20pter-p12 |
Pathway : | BARD1 signaling events; BRCA1-associated genome surveillance complex (BASC); Base excision repair |
Function : | DNA polymerase binding; DNA polymerase processivity factor activity; MutLalpha complex binding |
Products Types
◆ Recombinant Protein | ||
PCNA-066H | Recombinant Human PCNA Protein | +Inquiry |
PCNA-6556M | Recombinant Mouse PCNA Protein, His (Fc)-Avi-tagged | +Inquiry |
PCNA-626H | Recombinant Human PCNA Protein, MYC/DDK-tagged | +Inquiry |
PCNA-3148R | Recombinant Rhesus Macaque PCNA Protein, His (Fc)-Avi-tagged | +Inquiry |
Pcna-4715M | Recombinant Mouse Pcna Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
PCNA-500HCL | Recombinant Human PCNA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket