Recombinant Human TTR

• Cat.No.: TTR-11H
• Product Overview: Recombinant human TTR was produced from the codon-optimized synthetic gene in Trichoplusia ni larval expression system.

Specification

• Description: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Homotetramer. Interacts with RBP4. Defects in TTR are the cause of amyloidosis transthyretin-related; hyperthyroxinemia dystransthyretinemic euthyroidal; carpal tunnel syndrome type 1.
• Source: Trichoplusia ni larval expression system
• Species: Human
• Form: 1.8 mg/mL in 50 mM Tris buffer, 200 mM NaCl, pH 7.8, 0.2 μM Filtered.
• AA Sequence: GPTGTGESKC PLMVKVLDAV RGSPAINVAV HVFRKAADDT WEPFASGKTS ESGELHGLTT EEEFVEGIYK VEIDTKSYWK ALGISPFHEH AEVVFTANDS GPRRYTIAAL LSPYSYSTTA VVTNPKE
• Purity: >90% as determined by SDS-PAGE
• Storage: Store at -80°C or colder upon arrival. Freeze-thaw cycles of this product should be avoided.

Gene Information

• Gene Name: TTR transthyretin [ Homo sapiens ]
• Official Symbol: TTR
• Synonyms: CTS; CTS1; PALB; TBPA; HEL111; HsT2651; transthyretin; ATTR; carpal tunnel syndrome 1; thyroxine-binding prealbumin; epididymis luminal protein 111; prealbumin, amyloidosis type I
• Gene ID: 7276
• mRNA Refseq: NM_000371
• Protein Refseq: NP_000362
• MIM: 176300
• UniProt ID: P02766
• Chromosome Location: 18q12.1
• Pathway: Amyloids, organism-specific biosystem; Diseases associated with visual transduction, organism-specific biosystem; Signal Transduction, organism-specific biosystem; The canonical retinoid cycle in rods (twilight vision), organism-specific biosystem
• Function: hormone activity; hormone binding; identical protein binding