"VEGFA" Related Products

Recombinant Equine VEGFA

Cat.No.: VEGFA-209E
Product Overview: Recombinant Equine VEGFA was expressed in Yeast.
Description: Vascular endothelial growth factor (VEGF) proteins stimulate vasculogenesis and angiogenesis. They are part of the system that restores the oxygen supply to tissues when blood circulation is inadequate. The normal function of VEGF proteins is to create new blood vessels during embryonic development, new blood vessels after injury, muscle following exercise, and new vessels (collateral circulation) to bypass blocked vessels. The VEGF family has six members, including VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and Placental Growth Factor (PGF). Activity of VEGF-A, as its name implies, has been studied mostly on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g., stimulation monocyte/macrophage migration, neurons, cancer cells, kidney epithelial cells). In vitro, VEGF-A has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF-A is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor (VPF).
Source: Yeast
Species: Equine
Form: Lyophilized
Bio-activity: In testing
Molecular Mass: 19.2 kDa
AA Sequence: APMAEGEHKT HEVVKFMDVY QRSYCRPIET LVDIFQEYPD EIEYIFKPSC VPLMRCGGCC NDEGLECVPT AEFNITMQIM RIKPHQSQHI GEMSFLQHSK CECRPKKDKA RQENPCGPCS ERRKHLFVQD PQTCKCSCKN TDSRCKARQL ELNERTCRCD KPRR (164)
Purity: >95% as visualized by SDS-PAGE analysis.
Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Reconstitution: Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Gene Name: VEGFA vascular endothelial growth factor A [ Equus caballus (horse) ]
Official Symbol: VEGFA
Synonyms: VEGFA; vascular endothelial growth factor A; VPF; VEGF-A; vascular permeability factor; vascular endothelial growth factor 164
Gene ID: 100033839
mRNA Refseq: NM_001081821
Protein Refseq: NP_001075290
UniProt ID: Q9GKR0
Chromosome Location: 20
Pathway: HIF-1 signaling pathway; MicroRNAs in cancer; PI3K-Akt signaling pathway

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