"IL1B" Related Products

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Recombinant Human IL1B, His-tagged

Cat.No.: IL1B-60H
Product Overview: Recombinant Human Interleukin-1 beta, fused with C terminal His tag, was expressed in E. coli.
Description: Interleukin-1 (IL-1) is one of the first cytokines ever described. Its initial discovery was as a factor that could induce fever, control lymphocytes, increase the number of bone marrow cells and cause degeneration of bone joints. At this time, IL-1 was known under several other names including endogenous pyrogen, lymphocyte activating factor, haemopoetin-1 and mononuclear cell factor, amongst others.It was around 1984-1985 when scientists confirmed that IL-1 was actually composed of two distinct proteins, now called IL-1α and IL-1β.These belong to a family of cytokines known as the interleukin-1 superfamily.Both IL-1α and IL-1β are produced by macrophages, monocytes and dendritic cells.
Source: E. coli
Species: Human
Tag: His
Form: The protein solution is in 0.05M phosphate buffer containing 0.15M NaCl and 0.09% NaN3 pH 7.5. Filtered through a 0.4μM membrane.
Molecular Mass: 21.2kDa
Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
Purity: >95 % as determined by SDS-PAGE
Applications: Western blotting, ELISA
Storage: Store it under sterile conditions at -20℃ to -110℃ upon receiving.Recommend to aliquot the protein into smaller quantities for optimal storage.
Gene Name: IL1B interleukin 1, beta [ Homo sapiens ]
Official Symbol: IL1B
Synonyms: IL1B; interleukin 1, beta; interleukin-1 beta; IL 1B; IL1 BETA; IL1F2; IL-1 beta; catabolin; preinterleukin 1 beta; pro-interleukin-1-beta; IL-1; IL1-BETA;
Gene ID: 3553
mRNA Refseq: NM_000576
Protein Refseq: NP_000567
MIM: 147720
UniProt ID: P01584
Chromosome Location: 2q14
Pathway: African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Apoptosis, organism-specific biosystem;
Function: cytokine activity; cytokine activity; growth factor activity; interleukin-1 receptor binding; protein domain specific binding;

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