Recombinant Human glycoprotein Ibα, His-tagged, non-sulfated
Cat.No. : | GP1BA-19H |
Product Overview : | Recombinant human GP1BA, fused with an C-terminal hexahistidine tag, was expressed in HEK293-EBNA1 cells. In the native protein the tyrosine residues at positions 292, 294 and 295 are sulfated. In this product none of the three tyrosines are sulfated. |
- Specification
- Gene Information
- Related Products
Description : | Glycoprotein Ibα is part of the platelet receptor Glycoprotein Ib-XI-V complex. The Glycoprotein Ib-XI-V complex mediates binding of platelets to sites of vascular damage. This product consists of residues 17-306 of glycoprotein Ibα and contains the binding sites for Von Willebrand Factor, thrombin and botrocetin. The two N-linked glycoslation sites , Asn37 and Asn175, have been removed by mutation to glutamine. |
Source : | HEK293-EBNA1 cells |
Species : | Human |
Tag : | His |
Form : | PBS without preservative. |
Molecular Mass : | The calculated molecular weight of recombinant human GpIbα, residues 17-306, is 33.5 kDa. |
AA Sequence : | Residues 17-306 |
Storage : | - 80 °C (stable for at least 1 year). After thawing it should be stored in appropriate small aliquots at - 20 °C or - 80 °C (stable for at least 2 months). |
Gene Name : | GP1BA glycoprotein Ib (platelet), alpha polypeptide [ Homo sapiens ] |
Official Symbol : | GP1BA |
Synonyms : | GP1BA; glycoprotein Ib (platelet), alpha polypeptide; GP1B; platelet glycoprotein Ib alpha chain; CD42b; GP-Ib alpha; antigen CD42b-alpha; platelet membrane glycoprotein 1b-alpha subunit; BSS; VWDP; CD42B; GPIbA; BDPLT1; BDPLT3; DBPLT3; CD42b-alpha; MGC34595; |
Gene ID : | 2811 |
mRNA Refseq : | NM_000173 |
Protein Refseq : | NP_000164 |
MIM : | 606672 |
UniProt ID : | P07359 |
Chromosome Location : | 17pter-p12 |
Pathway : | ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; GP1b-IX-V activation signalling, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Hemostasis, organism-specific biosystem; |
Function : | protein binding; thrombin receptor activity; |
Products Types
◆ Recombinant Protein | ||
GP1BA-16H | Recombinant Human GP1BA Protein, His-tagged | +Inquiry |
GP1BA-531H | Recombinant Human GP1BA Protein (17-505 aa), His-tagged | +Inquiry |
GP1BA-2584H | Recombinant Human GP1BA protein(381-450 aa), N-SUMO & C-His-tagged | +Inquiry |
GP1BA-1401H | Recombinant Human GP1BA Protein (17-531 aa), His-tagged | +Inquiry |
GP1BA-5130H | Recombinant Human GP1BA Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
GP1BA-5823HCL | Recombinant Human GP1BA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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