Recombinant Human PARK7, MYC/DDK-tagged，C13 & N15-labeled

• Cat.No.: PARK7-231H
• Product Overview: C13 and N15-labeled Human PARK7 recombinant protein, fused with C-terminal MYC/DDK, was expressed in Human HEK293 cells.

Specification

• Description: The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
• Source: Human HEK293 cells
• Species: Human
• Tag: MYC/DDK
• Form: Liquid
• Molecular Mass: 19.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Storage: Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
• Concentration: > 50 ug/ml as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PARK7 parkinson protein 7 [ Homo sapiens (human) ]
• Official Symbol: PARK7
• Synonyms: PARK7; Parkinson disease (autosomal recessive, early onset) 7; DJ1; DJ-1; FLJ27376; FLJ34360; FLJ92274; Parkinson disease protein 7; oncogene DJ1; oncogene DJ1; protein DJ-1; OTTHUMP00000001350; OTTHUMP00000001351; OTTHUMP00000001348; OTTHUMP00000001349
• Gene ID: 11315
• mRNA Refseq: NM_001123377
• Protein Refseq: NP_001116849
• MIM: 602533
• UniProt ID: Q99497
• Chromosome Location: 1p36.23
• Pathway: Alpha-synuclein signaling; Androgen receptor signaling pathway; Parkinsons Disease Pathway
• Function: L-dopa decarboxylase activator activity; androgen receptor binding; NOT core promoter binding