Recombinant Human CD5 protein, His-tagged
Cat.No. : | CD5-175H |
Product Overview : | Recombinant Human CD5 (Arg25-Pro372) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Arg25 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 40.5 kDa. The protein migrates as 48-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Arg25-Pro372 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CD5 |
Official Symbol : | CD5 |
Synonyms : | CD5; CD5 molecule; CD5 antigen (p56 62) , LEU1; T-cell surface glycoprotein CD5; T1; CD5 antigen (p56-62); lymphocyte antigen T1/Leu-1; LEU1 |
Gene ID : | 921 |
mRNA Refseq : | NM_014207 |
Protein Refseq : | NP_055022 |
MIM : | 153340 |
UniProt ID : | P06127 |
Products Types
◆ Recombinant Protein | ||
Cd5-688R | Recombinant Rat Cd5 Protein, His-tagged | +Inquiry |
CD5-915R | Recombinant Rat CD5 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD5-0830H | Recombinant Human CD5 Protein, GST-Tagged | +Inquiry |
CD5-542H | Recombinant Human CD5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cd5-843M | Recombinant Mouse Cd5 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CD5-2498MCL | Recombinant Mouse CD5 cell lysate | +Inquiry |
CD5-1293RCL | Recombinant Rat CD5 cell lysate | +Inquiry |
CD5-2572HCL | Recombinant Human CD5 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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