Recombinant Human HK1, His-Twin Strep-tagged
Cat.No. : | HK1-177H |
Product Overview : | Recombinant Human HK1 /Hexokinase-1 Protein,C-Twin Strep & His Tag (rh HK1 /Hexokinase-1,Twin Strep) Asp 16 - Ser 917 (Accession # NP_000179) was produced in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Hexokinase-1 (HK1) is also known as Brain form hexokinase, Hexokinase type I (HK I). Hexokinase-1 is a monomer which can interact with RABL2/RABL2A. HK1 binds preferentially to GTP-bound RABL2 By similarity.HK1 interacts with VDAC1 and the HK1-VDAC1 complex interacts with ATF2. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Twin Strep |
Predicted N Terminal : | Asp 16 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 and some stabilizers. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Molecular Mass : | rh HK1 /Hexokinase-1,Twin Strep is fused with polyhistidine tagged Twin Strep Tag at the C-terminus, and has a calculated MW of 105 kDa. The predicted N-terminus is Asp 16. DTT-reduced Protein migrates as 95-115 kDa in SDS-PAGE. |
Endotoxin : | Less than 1.0 EU per μg of the rh HK1 /Hexokinase-1,Twin Strep by the LAL method. |
Purity : | >85% as determined by SDS-PAGE. |
Applications : | Recombinant Proteins |
Storage : | Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC). |
Gene Name : | HK1 hexokinase 1 [ Homo sapiens ] |
Official Symbol : | HK1 |
Synonyms : | HK1; hexokinase 1; hexokinase-1; HK I; glycolytic enzyme; hexokinase type I; brain form hexokinase; HKI; HXK1; HK1-ta; HK1-tb; HK1-tc; |
Gene ID : | 3098 |
mRNA Refseq : | NM_000188 |
Protein Refseq : | NP_000179 |
MIM : | 142600 |
UniProt ID : | P19367 |
Chromosome Location : | 10q22 |
Pathway : | Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Butirosin and neomycin biosynthesis, organism-specific biosystem; Butirosin and neomycin biosynthesis, conserved biosystem; Carbohydrate digestion and absorption, organism-specific biosystem; Carbohydrate digestion and absorption, conserved biosystem; Fructose and mannose metabolism, organism-specific biosystem; |
Function : | ATP binding; hexokinase activity; kinase activity; nucleotide binding; transferase activity; |
Products Types
◆ Recombinant Protein | ||
Hk1-1129M | Recombinant Mouse Hk1 Protein, MYC/DDK-tagged | +Inquiry |
HK1-2516R | Recombinant Rat HK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HK1-1141H | Active Recombinant Human HK1 Protein, His-tagged | +Inquiry |
HK1-318H | Recombinant Human HK1 Protein, MYC/DDK-tagged | +Inquiry |
HK1-2681H | Recombinant Human HK1 protein(21-460 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
HK1-794HCL | Recombinant Human HK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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