Active Human Haptoglobin Reference Standard

• Cat.No.: HP-14H

Specification

• Description: Haptoglobin is a positive acute phase protein that binds free hemoglobin and removes it from the circulation to prevent kidney injury, and iron lossfollowing hemolysis. Three major haptoglobinphenotypes are known to exist (Hp 1-1, Hp 2-1,and Hp 2-2). Hp 1-1 is biologically the most effective in binding free hemoglobin and suppressing inflammatory responses associated with free hemoglobin. Hp 2-2 is biologically the least active, and Hp 2-1 is moderately active.
• Species: Human
• Form: Liquid
• Bio-activity: The level of Haptoglobin in the serum was quantified using ELISA.
• Usage: For research use only, not for diagnostic or therapeutic use.
• Quality Control Test: Generated from a human serum pool. This lot has been tested by standard laboratory procedures and found to be negative for HIV 1, HIV 2, Hepatitis B and Hepatitis C.
• Storage: Stored at -20 °C, 4 °C for less than seven days, frozen for greater than seven days.
• Concentration: 1.31 mg/ml
• Preservative: 0.1% sodium azide

Gene Information

• Gene Name: HP haptoglobin [ Homo sapiens ]
• Official Symbol: HP
• Synonyms: HP; haptoglobin; zonulin; binding peptide; haptoglobin alpha(1S)-beta; haptoglobin alpha(2FS)-beta; haptoglobin, beta polypeptide; haptoglobin, alpha polypeptide; BP; HPA1S; HP2ALPHA2; MGC111141
• Gene ID: 3240
• mRNA Refseq: NM_001126102
• Protein Refseq: NP_001119574
• MIM: 140100
• UniProt ID: P00738
• Chromosome Location: 16q22.2
• Pathway: amb2 Integrin signaling, organism-specific biosystem
• Function: catalytic activity; hemoglobin binding; serine-type endopeptidase activity