Active Human Hemopexin Reference Standard

• Cat.No.: HPX-16H

Specification

• Description: Hemopexin binds heme with the highest affinity of any known protein. Its performs functions in scavenging the heme released or lost by the turnover of heme proteins such as hemoglobin, thus protects the body from the oxidative damage that free heme can cause. In addition, hemopexin releases its bound ligand for internalisation upon interacting with a specific receptor situated on the surface of liver cells, thus implicated in preservation of the body"s iron. High hemopexin levels indicate that there has been significant degradation of heme containing compounds and hemopexin is made to scavenge any heme it can, and high hemopexin levels are therefore one of the diagnostic features of a hemolytic anemia.
• Species: Human
• Form: Liquid
• Bio-activity: The level of Hemopexin in the serum was quantified using ELISA.
• Usage: For research use only, not for diagnostic or therapeutic use.
• Quality Control Test: Generated from a human serum pool. This lot has been tested by standard laboratory procedures and found to be negative for HIV 1, HIV 2, Hepatitis B and Hepatitis C.
• Storage: Stored at -20 °C, 4 °C for less than seven days, frozen for greater than seven days.
• Concentration: 1.16 mg/ml
• Preservative: 0.1% sodium azide

Gene Information

• Gene Name: HPX hemopexin [ Homo sapiens ]
• Official Symbol: HPX
• Synonyms: HPX; hemopexin; beta-1B-glycoprotein; HX; FLJ56652
• Gene ID: 3263
• mRNA Refseq: NM_000613
• Protein Refseq: NP_000604
• MIM: 142290
• UniProt ID: P02790
• Chromosome Location: 11p15.5-p15.4
• Function: binding; heme transporter activity; metal ion binding; protein binding