Recombinant Human FLT3, His tagged

Cat.No.: FLT3-2244H
Product Overview: Recombinant Human Fms-Related Tyrosine Kinase 3 Ligand/FLT3LG is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (T27-P184) of Human FLT3LG fused with a polyhistidine tag at the C-terminus.
Description: Fms-Related Tyrosine Kinase 3 Ligand (FLT3LG) is a hematopoietic four helical bundle cytokine. It is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). In synergy with other growth factors, Flt3 ligand stimulates the proliferation and differentiation of various blood cell progenitors by activiation of Flt 3 receptor.
Source: HEK293
Species: Human
Tag: His
Bio-activity: >1.0 x 10^6 U/mg
Endotoxin: Less than 0.1 EU/μg.
Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Storage: Store at< -20°c, stable for 6 months after receipt. please minimize freeze-thaw>
Gene Name: FLT3 fms-related tyrosine kinase 3 [ Homo sapiens ]
Official Symbol: FLT3
Synonyms: FLT3; fms-related tyrosine kinase 3; receptor-type tyrosine-protein kinase FLT3; CD135; FLK2; STK1; STK-1; CD135 antigen; FL cytokine receptor; fetal liver kinase 2; fms-like tyrosine kinase 3; stem cell tyrosine kinase 1; growth factor receptor tyrosine kinase type III; FLK-2;
Gene ID: 2322
mRNA Refseq: NM_004119
Protein Refseq: NP_004110
MIM: 136351
UniProt ID: P36888
Chromosome Location: 13q12
Pathway: Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Pathways in cancer, organism-specific biosystem;
Function: ATP binding; cytokine receptor activity; nucleotide binding; phosphatidylinositol 3-kinase binding; protein homodimerization activity; receptor activity; transmembrane receptor protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor-activated receptor activity;

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