"POLRMT" Related Products

Recombinant Human POLRMT

Cat.No.: POLRMT-1854H
Product Overview: Recombinant Human POLRMT is purified from E. coli and does not incorporate an affinity tag.
Description: This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes.
Source: E. coli
Species: Human
Storage: Stable for 6 months at -80°C from date of shipment. Working stocks may be stored at -20°C.
Concentration: 0.5 mg/mL in 10 mM Tris (pH 8.0), 1 mM DTT, 100 mM NaCl and 20% glycerol.
Gene Name: POLRMT polymerase (RNA) mitochondrial (DNA directed) [ Homo sapiens ]
Official Symbol: POLRMT
Synonyms: POLRMT; polymerase (RNA) mitochondrial (DNA directed); DNA-directed RNA polymerase, mitochondrial; APOLMT; h mtRPOL; MTRNAP; MTRPOL; h-mtRPOL; NP_005026.3; EC 2.7.7.6
Gene ID: 5442
mRNA Refseq: NM_005035
Protein Refseq: NP_005026
MIM: 601778
UniProt ID: O00411
Chromosome Location: 19p13.3
Pathway: Gene Expression; Mitochondrial biogenesis; Mitochondrial Gene Expression
Function: DNA binding; DNA-directed RNA polymerase activity; poly(A) RNA binding

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