Human Plasminogen Activator Inhibitor-1 (PAI-1), plasma Reference standard

• Cat.No.: SERPINE1-122H
• Product Overview: The Standard consists of reactivated recombinant (in Chinese hamster ovary cells) PAI-1 added to normal human plasma and lyophilized following ampouling.

Specification

• Source: Chinese hamster ovary cells
• Species: Human
• Usage: Allow ampoules to warm to room temperature. Open ampoule, taking care to ensure that all material is in the lower part, and reconstitute with 1.0ml distilled water.
• Notes: This preparation is not for administration to humans. The preparation contains material of human origin, and either the final product or the source materials, from which it is derived, have been tested and found negative for HBsAg, anti-HIV and HCV RNA. As with all materials of biological origin, this preparation should be regarded as potentially hazardous to health. It should be used and discarded according to your own laboratorys safety procedures. Such safety procedures should include the wearing of protective gloves and avoiding the generation of aerosols. Care should be exercised in opening ampoules or vials, to avoid cuts.
• Stability: Reference materials are held at Creative Biomart within assured, temperature- controlled storage facilities. Reference Materials should be stored on receipt as indicated on the label.
• Storage: Unopened ampoules should be stored in the dark at or below - 20°C. Please note: because of the inherent stability of lyophilized material, Creative Biomart may ship these materials at ambient temperature.

Gene Information

• Gene Name: SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 [ Homo sapiens ];
• Official Symbol: SERPINE1
• Synonyms: SERPINE1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; PAI1, PLANH1, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; plasminogen activator inhibitor 1; PAI; plasminogen activator inhibitor; type I; serpin E1; endothelial plasminogen activator inhibitor; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; PAI1; PAI-1; PLANH1
• Gene ID: 5054
• mRNA Refseq: NM_000602
• Protein Refseq: NP_000593
• MIM: 173360
• UniProt ID: P05121
• Chromosome Location: 7q21.3-q22
• Pathway: Adipogenesis, organism-specific biosystem; BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Blood Clotting Cascade, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Circadian Clock, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem
• Function: peptidase inhibitor activity; protease binding; protein binding; contributes_to receptor binding; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity