Recombinant Human Constitutive androstane receptor Hsp90 complex, GST-tagged
Cat.No. : | NR1I3-108H |
Product Overview : | Recombinant Human GST-tagged Constitutive androstane receptor (CAR) consists of a 218 a.a. GST tag, a 13 a.a. flexible linker and 352 a.a. human CAR, Acc# NP_001070948. Human Constitutive androstane receptor ligand-binding domain (CAR) in complex with human Hsp90 was produced in insect cells co-infected with two recombinant baculoviruses. GST tagged CAR and Hsp90 are the major components of the complex. |
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- Gene Information
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Description : | Constitutive androstane receptor is also known as nuclear receptor subfamily 1, group I, member 3 (NR1I3). In the cytoplasm it is found in complexes with Hsp90 which suggests its involvement in the receptor function. |
Source : | Sf9 insect cells |
Species : | Human |
Tag : | GST |
Form : | 20 mM Na-P pH 8.0, 40 mM KCl, 20 mM Na2MoO4, 7 mM reduced glutathione, 15% glycerol. |
Purity : | >70% |
Applications : | Ligand binding and coactivator peptide recruitment assays. |
Storage : | Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice. |
Gene Name : | NR1I3 nuclear receptor subfamily 1, group I, member 3 [ Homo sapiens ] |
Official Symbol : | NR1I3 |
Synonyms : | NR1I3; nuclear receptor subfamily 1, group I, member 3; nuclear receptor subfamily 1 group I member 3; CAR; CAR1; constitutive androstane receptor; MB67; constitutive active receptor; constitutive active response; orphan nuclear receptor MB67; orphan nuclear hormone receptor; constitutive activator of retinoid response; constitutive androstane nuclear receptor variant 2; constitutive androstane nuclear receptor variant 3; constitutive androstane nuclear receptor variant 4; constitutive androstane nuclear receptor variant 5; MGC97144; MGC97209; MGC150433; |
Gene ID : | 9970 |
mRNA Refseq : | NM_001077469 |
Protein Refseq : | NP_001070937 |
MIM : | 603881 |
Chromosome Location : | 1q23.3 |
Pathway : | Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Nuclear receptors in lipid metabolism and toxicity, organism-specific biosystem; |
Function : | DNA binding; androgen receptor activity; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; thyroid hormone receptor activity; transcription coactivator activity; zinc ion binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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