Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human Constitutive androstane receptor Hsp90 complex, GST-tagged

Cat.No. : NR1I3-108H
Product Overview : Recombinant Human GST-tagged Constitutive androstane receptor (CAR) consists of a 218 a.a. GST tag, a 13 a.a. flexible linker and 352 a.a. human CAR, Acc# NP_001070948. Human Constitutive androstane receptor ligand-binding domain (CAR) in complex with human Hsp90 was produced in insect cells co-infected with two recombinant baculoviruses. GST tagged CAR and Hsp90 are the major components of the complex.
  • Specification
  • Gene Information
  • Related Products
Description : Constitutive androstane receptor is also known as nuclear receptor subfamily 1, group I, member 3 (NR1I3). In the cytoplasm it is found in complexes with Hsp90 which suggests its involvement in the receptor function.
Source : Sf9 insect cells
Species : Human
Tag : GST
Form : 20 mM Na-P pH 8.0, 40 mM KCl, 20 mM Na2MoO4, 7 mM reduced glutathione, 15% glycerol.
Purity : >70%
Applications : Ligand binding and coactivator peptide recruitment assays.
Storage : Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.
Gene Name : NR1I3 nuclear receptor subfamily 1, group I, member 3 [ Homo sapiens ]
Official Symbol : NR1I3
Synonyms : NR1I3; nuclear receptor subfamily 1, group I, member 3; nuclear receptor subfamily 1 group I member 3; CAR; CAR1; constitutive androstane receptor; MB67; constitutive active receptor; constitutive active response; orphan nuclear receptor MB67; orphan nuclear hormone receptor; constitutive activator of retinoid response; constitutive androstane nuclear receptor variant 2; constitutive androstane nuclear receptor variant 3; constitutive androstane nuclear receptor variant 4; constitutive androstane nuclear receptor variant 5; MGC97144; MGC97209; MGC150433;
Gene ID : 9970
mRNA Refseq : NM_001077469
Protein Refseq : NP_001070937
MIM : 603881
Chromosome Location : 1q23.3
Pathway : Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Nuclear receptors in lipid metabolism and toxicity, organism-specific biosystem;
Function : DNA binding; androgen receptor activity; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; thyroid hormone receptor activity; transcription coactivator activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All NR1I3 Products

Required fields are marked with *

My Review for All NR1I3 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends