Recombinant Human Retinoic acid receptor beta, GST-tagged

• Cat.No.: RARB-112H
• Product Overview: Recombinant Human GST-tagged Retinoic acid receptor beta ligand-binding domain (RARB-LBD) consists of a 218 a.a. GST tag, a 14 a.a. flexible linker and a 281 a.a. RARB-LBD, Acc# AAH60794.1, amino acids 168-448. GST tagged RARB-LBD was expressed in baculovirus-infected insect cells and purified using affinity chromatography.

Specification

• Description: Retinoic acid receptor beta (RAR-beta or RARB) is also known as NR1B2 (nuclear receptor subfamily 1, group B, member 2).
• Source: Sf9 insect cells
• Species: Human
• Tag: GST
• Form: 20 mM Na-P pH 8.0, 40 mM KCl, 20 mM Na2MoO4, 7 mM reduced glutathione, 15% glycerol.
• Purity: >90%
• Applications: Ligand binding and coactivator peptide recruitment assays.
• Storage: Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.

Gene Information

• Gene Name: RARB retinoic acid receptor, beta [ Homo sapiens ]
• Official Symbol: RARB
• Synonyms: RARB; retinoic acid receptor, beta; retinoic acid receptor beta; HAP; NR1B2; RRB2; RAR-beta; RAR-epsilon; HBV-activated protein; retinoic acid receptor beta 2; retinoic acid receptor beta 4; retinoic acid receptor beta 5; hepatitis B virus activated protein; retinoic acid receptor beta variant 1; retinoic acid receptor beta variant 2; retinoic acid receptor, beta polypeptide; nuclear receptor subfamily 1 group B member 2; MGC97363
• Gene ID: 5915
• mRNA Refseq: NM_000965
• Protein Refseq: NP_000956
• MIM: 180220
• UniProt ID: P10826
• Chromosome Location: 3p24
• Pathway: Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Non-small cell lung cancer, organism-specific biosystem; Non-small cell lung cancer, conserved biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Nuclear receptors in lipid metabolism and toxicity, organism-specific biosystem
• Function: DNA binding; metal ion binding; receptor activity; retinoic acid receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; zinc ion binding