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Recombinant Human RXRG, GST-tagged

Cat.No. : RXRG-120H
Product Overview : Recombinant Human GST-tagged RXR-gamma ligand-binding domain (RXRG-LBD) consists of a 218 a.a. GST tag, a 14 a.a. flexible linker and a 247 a.a. RXRG-LBD, Acc# NP_008848.1, amino acids 217-463, was expressed in baculovirus-infected insect cells and purified using affinity chromatography.
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  • Gene Information
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Description : Retinoid X receptor gamma (RXR-gamma or RXRG) is also known as NR2B3 (nuclear receptor subfamily 2, group B, member 3).
Source : Sf9 insect cells
Species : Human
Tag : GST
Form : 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, 3 mM Dithiothreitol, 7 mM reduced glutathione, 20% glycerol.
Purity : >90%
Applications : Ligand binding and coactivator peptide recruitment assays.
Storage : Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.
Gene Name : RXRG retinoid X receptor, gamma [ Homo sapiens ]
Official Symbol : RXRG
Synonyms : RXRG; retinoid X receptor, gamma; retinoic acid receptor RXR-gamma; NR2B3; nuclear receptor subfamily 2 group B member 3; RXRC;
Gene ID : 6258
mRNA Refseq : NM_001256570
Protein Refseq : NP_001243499
MIM : 180247
UniProt ID : P48443
Chromosome Location : 1q22-q23
Pathway : Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Non-small cell lung cancer, organism-specific biosystem; Non-small cell lung cancer, conserved biosystem;
Function : 9-cis retinoic acid receptor activity; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How do variations in the RXRG gene affect its function and contribute to disease? 03/28/2023

Genetic mutations in RXRG can disrupt its regulatory roles, leading to various developmental and metabolic disorders.

What is the significance of RXRG in the regulation of metabolic pathways and homeostasis? 06/28/2022

RXRG is key in regulating lipid and glucose metabolism, playing a role in metabolic homeostasis.

What role does RXRG play in developmental processes and organogenesis? 12/19/2021

RXRG is essential in embryonic development and organ formation, guiding cell fate decisions.

What is the primary function of RXRG in cellular signaling and gene regulation? 03/04/2021

RXRG functions as a nuclear receptor, regulating gene expression in response to ligand binding.

What potential does RXRG have as a therapeutic target in metabolic and degenerative diseases? 11/18/2019

Targeting RXRG in therapy offers potential in treating metabolic syndromes and degenerative diseases.

How does RXRG interact with retinoids and what is its role in vitamin A metabolism? 12/18/2017

It interacts with retinoids to modulate vitamin A metabolism, influencing cellular differentiation and proliferation.

How does RXRG contribute to the immune system's function and response? 07/08/2017

It influences immune function by affecting the development and differentiation of immune cells.

Customer Reviews (3)

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Reviews
05/07/2018

    Aids in groundbreaking discoveries, highly recommended.

    12/29/2017

      Outstanding protein analysis, a research asset.

      08/01/2017

        Enables data-driven decisions in our research.

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