Recombinant Human TOLLIP, GST-tagged
Cat.No. : | TOLLIP-151H |
Product Overview : | Recombinant human TOLLIP (amino acid residues 1-274), with N-terminal GST, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | TOLLIP has an N-Terminal TOM1 binding domain (TBD) that mediates protein-protein interactions, a C2 domain that targets TOLLIP to the endosome and a C-terminal CUE domain that binds mono-ubiquitin (Lo et al., 2009). Recent studies have proposed that Interleukin 1B (IL-1B) stimulation of HEK293 cells induces aggregation of Interleukin 1 Receptors (IL-1Rs) and recruitment of MYD88 followed by the TOLLIP/IL-1 receptor-associated kinase 1 (IRAK1) complex. |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Form : | 50 mM HEPES pH 7.5, 150 mM sodium chloride, 2 mM dithiothreitol, 10% glycerol |
Molecular Mass : | ~57kDa |
Purity : | >90% by InstantBlue™ SDS-PAGE |
Storage : | 12 months at -70°C. Avoid multiple freeze/thaw cycles. |
Concentration : | 0.5 mg/ml |
Gene Name : | TOLLIP toll interacting protein [ Homo sapiens ] |
Official Symbol : | TOLLIP |
Synonyms : | TOLLIP; toll interacting protein; toll-interacting protein; IL 1RAcPIP; adapter protein; IL-1RAcPIP; FLJ33531; |
Gene ID : | 54472 |
mRNA Refseq : | NM_019009 |
Protein Refseq : | NP_061882 |
MIM : | 606277 |
UniProt ID : | Q9H0E2 |
Chromosome Location : | 11p |
Pathway : | Cytokine Signaling in Immune system, organism-specific biosystem; IL1-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem; Signaling by Interleukins, organism-specific biosystem; Toll-like receptor signaling pathway, organism-specific biosystem; Toll-like receptor signaling pathway, organism-specific biosystem; |
Function : | Toll-like receptor binding; kinase binding; protein binding; signal transducer activity; |
Products Types
◆ Recombinant Protein | ||
TOLLIP-5872R | Recombinant Rat TOLLIP Protein, His (Fc)-Avi-tagged | +Inquiry |
TOLLIP-2231H | Recombinant Human TOLLIP Protein, His (Fc)-Avi-tagged | +Inquiry |
TOLLIP-2312H | Recombinant Human TOLLIP Protein, MYC/DDK-tagged | +Inquiry |
Tollip-6578M | Recombinant Mouse Tollip Protein, Myc/DDK-tagged | +Inquiry |
TOLLIP-4702R | Recombinant Rhesus Macaque TOLLIP Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TOLLIP-1806HCL | Recombinant Human TOLLIP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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