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Recombinant Chicken ACSL1

Cat.No. : ACSL1-1950C
Product Overview : Recombinant Chicken ACSL1 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Chicken
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC.
Storage Buffer : PBS buffer
Gene Name : ACSL1 acyl-CoA synthetase long-chain family member 1 [ Gallus gallus (chicken) ]
Official Symbol : ACSL1
Gene ID : 422547
Protein Refseq : NP_001012596
UniProt ID : Q5F420

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What is the relationship between ACSL1 and the gut microbiome? 11/30/2021

ACSL1 has been shown to be involved in the regulation of the gut microbiome by modulating the composition of the microbial community and the production of microbial metabolites. It is thought to do this by altering the availability of fatty acids and other nutrients in the gut environment.

What is the role of ACSL1 in mitochondrial function? 09/08/2021

ACSL1 is involved in the regulation of mitochondrial function by modulating the production of reactive oxygen species (ROS) and the activity of the electron transport chain. It has been shown to be important for the maintenance of mitochondrial membrane potential and energy production in cells.

What inhibitors have been developed to target ACSL1? 03/18/2021

Several inhibitors of ACSL1 have been developed, including triacsin C and thioesterase inhibitors such as N-arylthiourea and dithioester analogs. These inhibitors have shown promise in preclinical studies as potential therapeutics for metabolic diseases and cancer.

How does ACSL1 contribute to the regulation of lipid metabolism during fasting? 11/14/2020

ACSL1 is upregulated in response to fasting and is thought to contribute to the regulation of lipid metabolism during this time by promoting the oxidation of fatty acids for energy production and the synthesis of ketone bodies.

What diseases or disorders are associated with mutations in the ACSL1 gene? 10/04/2020

Mutations in the ACSL1 gene have been associated with a variety of diseases and disorders, including obesity, diabetes, and non-alcoholic fatty liver disease.

How is the activity of ACSL1 regulated by phosphorylation? 09/13/2019

ACSL1 can be phosphorylated by various kinases, such as PKC and AMPK, which can alter its activity and localization. Phosphorylation of ACSL1 has been shown to decrease its activity and promote its translocation from the cytoplasm to the nucleus.

What is the mechanism of action of triacsin C, an inhibitor of ACSL1? 07/06/2019

Triacsin C inhibits the activity of ACSL1 by binding to its acyl-CoA binding site and preventing the formation of the acyl-adenylate intermediate. This prevents the conversion of fatty acids to their acyl-CoA derivatives, leading to a decrease in lipid synthesis and storage.

What is the role of ACSL1 in the synthesis of eicosanoids? 09/01/2018

ACSL1 plays a role in the synthesis of eicosanoids, which are important signaling molecules involved in a variety of physiological processes, such as inflammation and blood clotting. ACSL1 is involved in the activation of arachidonic acid, a precursor of eicosanoids, by converting it to arachidonyl-CoA.

How is ACSL1 involved in the regulation of inflammation? 06/03/2018

ACSL1 has been shown to be involved in the regulation of inflammation by modulating the production of pro-inflammatory mediators, such as cytokines and chemokines. It is thought to do this by altering the lipid composition of cellular membranes and influencing the signaling pathways involved in inflammation.

How is ACSL1 involved in the regulation of lipid droplet formation? 05/14/2018

ACSL1 has been shown to be involved in the regulation of lipid droplet formation by promoting the esterification of fatty acids to neutral lipids, which can then be stored in lipid droplets. It has also been shown to interact with other proteins.

Customer Reviews (5)

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Reviews
10/11/2021

    Outstanding quality and service. Would give 10 stars if I could.

    10/16/2020

      The recombinant protein worked perfectly for my experiment. Thank you!

      07/23/2019

        Excellent value for the price. Will be a repeat customer.

        12/03/2018

          Thank you for providing such a great product.

          03/03/2018

            I've ordered from many suppliers in the past, but this company stands out for its exceptional quality and service.

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