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Recombinant Chicken RAD51

Cat.No. : RAD51-6728C
Product Overview : Recombinant Chicken RAD51 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Chicken
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC.
Storage Buffer : PBS buffer
Gene Name : RAD51 RAD51 recombinase [ Gallus gallus (chicken) ]
Official Symbol : RAD51
Gene ID : 396086
Protein Refseq : NP_990504
UniProt ID : P37383

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does RAD51 contribute to the homologous recombination (HR) repair pathway? 10/24/2021

In the HR pathway, RAD51 forms nucleoprotein filaments on single-stranded DNA, allowing it to search for and invade a homologous DNA sequence, facilitating accurate DNA repair.

Are there any known interactions between RAD51 and BRCA proteins? 05/02/2021

Yes, RAD51 interacts with BRCA proteins, especially BRCA2. This interaction is crucial for the proper function of RAD51 in the HR pathway.

Are there any diseases or conditions associated with RAD51 dysregulation or mutations? 10/17/2020

While mutations in RAD51 are rare, dysregulation of its function can contribute to genomic instability. Some mutations in RAD51 have been linked to increased cancer susceptibility.

What is the primary function of RAD51 in DNA repair mechanisms? 05/27/2020

RAD51 plays a central role in the DNA repair mechanism, specifically in homologous recombination (HR), where it facilitates the search for homology and strand pairing.

How is RAD51 recruited to sites of DNA damage? 06/01/2018

RAD51 is recruited to sites of DNA damage through interactions with various mediator proteins, including BRCA2, which helps load RAD51 onto single-stranded DNA regions.

Can RAD51 activity be targeted therapeutically in cancer treatments? 06/01/2018

Yes, RAD51's activity can be targeted therapeutically. Inhibiting RAD51 can sensitize cancer cells to DNA-damaging agents, making it a potential target in combination cancer therapies, especially for tumors with defective DNA repair pathways.

How does RAD51's function compare to that of its paralogs, like RAD51B, RAD51C, etc.? 05/09/2018

RAD51 has several paralogs, including RAD51B, RAD51C, RAD51D, XRCC2, and XRCC3. While they all play roles in HR, each has distinct functions and interactions, with some acting as mediators or stabilizers of RAD51's nucleoprotein filament.

Customer Reviews (3)

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Reviews
09/05/2022

    User-friendly protocol included.

    03/14/2022

      Affordable price, great value.

      01/03/2022

        Product met all specifications.

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