Recombinant Human Dickkopf Homolog 1 (Xenopus laevis), His-tagged
Cat.No. : | DKK1-347H |
Product Overview : | Recombinant human Dkk-1 protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography (253 aa, 27.8 kDa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | DKK1-347H |
Description : | Dickkopf-related protein 1, also known as Dkk-1, is a member of the Dkk protein family including Dkk-1, 2, 3 and -4. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated level of Dkk-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. |
Source : | Hi-5 cell. |
Formulation : | Liquid. In PBS (pH 7.4) containing 10% glycerol. |
Molecular Weight : | 27.8 kDa (253 aa). |
Purity : | > 85% by SDS – PAGE. |
Concentration : | 0.25 mg/ml (determined by Bradford assay). |
Endotoxin Level : | < 1.0 EU per 1 μg of protein (determined by LAL method). |
Sequence : | ADPTLNSVLN SNAIKNLPPP LGGAAGHPGS AVSAAPGILY PGGNKYQTID NYQPYPCAED EECGTDEYCA SPTRGGDAGV QICLACRKRR KRCMRHAMCC PGNYCKNGIC VSSDQNHFRG EIEETITESF GNDHSTLDGY SRRTTLSSKM YHTKGQEGSV CLRSSDCASG LCCARHFWSK ICKPVLKEGQ VCTKHRRKGS HGLEIFQRCY CGEGLSCRIQ KDHHQASNSS RLHTCQRHSG RLVPRGSHHH HHH |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | DKK1 |
Synonyms : | DKK1; dickkopf homolog 1 (Xenopus laevis); SK; DKK-1; Dickkopf-1; Dkk-1; hDkk-1; OTTHUMP00000019617; dickkopf homolog 1; dickkopf (Xenopus laevis) homolog 1; dickkopf-1 like; dickkopf related protein-1; DKK1 dickkopf homolog 1 (Xenopus laevis). |
Gene ID : | 22943 |
mRNA Refseq : | NM_012242.2 |
Protein Refseq : | NP_036374.1 |
MIM : | 605189 |
UniProt ID : | O94907 |
Chromosome Location : | 10q11.2 |
Pathway : | Wnt signaling pathway. |
Function : | growth factor activity; low-density lipoprotein receptor binding; protein binding; signal transducer activity. |
Products Types
◆ Recombinant Protein | ||
DKK1-1098R | Recombinant Rhesus Macaque DKK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Dkk1-197M | Recombinant Mouse Dkk1 Protein, His-tagged | +Inquiry |
DKK1-430D | Active Recombinant Human DKK1 Protein | +Inquiry |
Dkk1-1534R | Recombinant Rat Dkk1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Dkk1-678R | Active Recombinant Rat Dkk1 protein(Met1-His270), His-tagged | +Inquiry |
◆ Lysates | ||
DKK1-2622RCL | Recombinant Rhesus DKK1 cell lysate | +Inquiry |
DKK1-2983HCL | Recombinant Human DKK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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