| Description : |
The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. |
| Source : |
Wheat germ |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
143.55 kDa |
| AA Sequence : |
MPAIMTMLADHAARQLLDFSQKLDI NLLDNVVNCLYHGEGAQQRMAQEVL THLKEHPDAWTRVDTILEFSQNMNT KYYGLQILENVIKTRWKILPRNQCE GIKKYVVGLIIKTSSDPTCVEKEKV YIGKLNMVLVQILKQEWPKHWPTFI SDIVGASRTSESPCQNNMVILKLLS EEVFDFSSGQITQVKSKHLKDSMCN EFSQIFQLCQFVMENSQNAPLVHAT LETLLRFLNWIPLGYIFETKLISTL IYKFLNVPMFRNVSLKCLTEIAGVS VSQYEEQFVTLFTLTMMQLKQMLPL NTNIRLAYSNGKDDEQNFIQNLSLF LCTFLKEHDQLIEKRLNLRETLMEA LHYMLLVSEVEETEIFKICLEYWNH LAAELYRESPFSTSASPLLSGSQHF DVPPRRQLYLPMLFKVRLLMVSRMA KPEEVLVVENDQGEVVREFMKDTDS INLYKNMRETLVYLTHLDYVDTERI MTEKLHNQVNGTEWSWKNLNTLCWA IGSISGAMHEEDEKRFLVTVIKDLL GLCEQKRGKDNKAIIASNIMYIVGQ YPRFLRAHWKFLKTVVNKLFEFMHE THDGVQDMACDTFIKIAQKCRRHFV QVQVGEVMPFIDEILNNINTIICDL QPQQVHTFYEAVGYMIGAQTDQTVQ EHLIEKYMLLPNQVWDSIIQQATKN VDILKDPETVKQLGSILKTNVRACK AVGHPFVIQLGRIYLDMLNVYKCLS ENISAAIQANGEMVTKQPLIRSMRT VKRETLKLISGWVSRSNDPQMVAEN FVPPLLDAVLIDYQRNVPAAREPEV LSTMAIIVNKLGGHITAEIPQIFDA VFECTLNMINKDFEEYPEHRTNFFL LLQAVNSHCFPAFLAIPPTQFKLVL DSIIWAFKHTMRNVADTGLQILFTL LQNVAQEEAAAQSFYQTYFCDILQH IFSVVTDTSHTAGLTMHASILAYMF NLVEEGKISTSLNPGNPVNNQIFLQ EYVANLLKSAFPHLQDAQVKLFVTG LFSLNQDIPAFKEHLRDFLVQIKEF AGEDTSDLFLEEREIALRQADEEKH KRQMSVPGIFNPHEIPEEMCD |
| Applications : |
ELISA; WB-Re; AP; Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
