"EIF5A" Related Products

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Recombinant Human Eukaryotic Translation Initiation Factor 5A

Cat. No.: EIF5A-362H
Product Overview: Recombinant human eIF5A protein was expressed in E. coli and purified by using conventional chromatography techniques, 16.8 kDa (154 aa).
Description: Eukaryotic translation initiation factor 5A (eIF5A) is the only protein Known to contain unusual amino acid formed by the action of deoxyhypusine synthase and deoxyhypusine hydroxylase using spermidine as the substrate. This protein was previously reported to be involved in the first step of peptide bond formation in translation; however more recent work implicates it as a universally conserved translation elongation factor. Modulation of eIF5A has been linked to proliferation and cancer.
Source: Escherichia Coli.
Form: Liquid. In 50 mM Tris-HCl buffer pH 7.5 containing 10 % glycerol
Purity: > 95% by SDS - PAGE.
Concentration: 1 mg/ml (determined by Bradford assay)
Sequences of amino acids: MADDLDFETG DAGASATFPM QCSALRKNGF VVLKGRPCKI VEMSTSKTGK HGHAKVHLVG IDIFTGKKYE DICPSTHNMD VPNIKRNDFQ LIGIQ DG YL S LLQDSGEVRE DLRLPEGDLG KEIEQKYDCG EEILITVLSA MTEEAAVAIK AMAK
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: EIF5A eukaryotic translation initiation factor 5A [ Homo sapiens ]
Synonyms: EIF5A; EIF-5A; EIF5A1; MGC104255; MGC99547; uORF; uORF A; eukaryotic translation initiation factor 5A; OTTHUMP00000128384; eIF-4D; eIF-5A; eIF-5A-1; eIF-5A1; eIF5AI; Eukaryotic initiation factor 5A isoform 1; Rev-binding factor.
Gene ID: 1984
mRNA Refseq: NM_001143760
Protein Refseq: NP_001137232
MIM: 600187
UniProt ID: P63241
Chromosome Location: 17p13-p12
Function: RNA binding; U6 snRNA binding; protein N-terminus binding; ribosome binding; translation elongation factor activity; translation initiation factor activity.

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