Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human Slow Cardiac Myosin Regulatory light chain 2, His-tagged

Cat.No. : MYL2-388H
Product Overview : Recombinant human MYL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques, 20.9 kDa (186aa)
  • Specification
  • Gene Information
  • Related Products
Cat. No. : MYL2-388H
Description : Myosin, light chain 2 (MYL2) encodes the regulatory light chain associated with cardiac myosin beta heavy chain. It is an important protein involved in the regulation of myosin ATPase activity in smooth muscle and Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MAPKKAKKRA GGANSNVFSM FEQTQIQEFK EAFTIMDQNR DGFIDKNDLR DTFAALGRVN VKNEEIDEMI KEAPGPINFT VFLTMFGEKL KGADPEETIL NAFKVFDPEG KGVLKADYVR EMLTTQAERF SKEEVDQMFA AFPPDVTGNL DYKNLVHIIT HGEEKD
Formulation : Liquid in 20mM Tris-HCl (pH 8.0) containing 20% glycerol 5mM CaCl2
Purity : > 95% by SDS PAGE
Concentration : 0.5 mg/ml (determined by Bradford assay)
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : MYL2 myosin, light chain 2, regulatory, cardiac, slow [ Homo sapiens ]
Synonyms : MYL2; myosin, light chain 2, regulatory, cardiac, slow; MLC2; CMH10; DKFZp779C0562; MYL2; slow cardiac myosin regulatory light chain 2; RLC of myosin; myosin light chain 2; regulatory light chain of myosin; cardiac ventricular myosin light chain 2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform; MLC-2v; myosin regulatory light chain 2, ventricular/cardiac muscle isoform
Gene ID : 4633
mRNA Refseq : NM_000432
Protein Refseq : NP_000423
MIM : 160781
UniProt ID : P10916
Chromosome Location : 12q24.11
Function : actin monomer binding; calcium ion binding; motor activity ;myosin heavy chain binding; protein binding; structural constituent of muscle

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
Are there any gender or age-related differences in MYL2 protein expression in cardiac muscle? 07/21/2022

Studies suggest that MYL2 expression levels may vary with age and gender, which could have implications for understanding cardiac health across different demographics.

Can MYL2 be used as a prognostic marker for predicting outcomes in cardiac patients? 06/08/2022

Elevated MYL2 levels may be indicative of a poorer prognosis in certain cardiac conditions, providing valuable information for treatment planning.

What role does MYL2 play in personalized medicine for cardiac patients? 12/09/2017

Understanding the genetic variations in MYL2 allows for personalized treatment strategies tailored to an individual's specific cardiac profile.

How does MYL2 contribute to the understanding of the molecular mechanisms underlying cardiac hypertrophy? 07/10/2017

Dysregulation of MYL2 is implicated in hypertrophic cardiomyopathy, contributing to our understanding of the molecular pathways leading to cardiac hypertrophy.

How can MYL2 protein analysis aid in risk stratification for cardiovascular diseases? 03/31/2017

Analyzing MYL2 variants and expression levels can help identify individuals at a higher risk of developing cardiac disorders, allowing for proactive management.

Customer Reviews (3)

Write a review
Reviews
04/09/2017

    The MYL2 Protein comes highly recommended for its exceptional performance, particularly in ELISA assays.

    11/02/2016

      This protein has proven to be of great utility in protein electron microscopy structure analysis.

      09/19/2016

        Researchers utilizing the MYL2 Protein can rely on its robust and reproducible performance in a variety of experimental settings.

        Ask a Question for All MYL2 Products

        Required fields are marked with *

        My Review for All MYL2 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends