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Recombinant Zebrafish ARCN1B

Cat.No. : ARCN1B-11571Z
Product Overview : Recombinant Zebrafish ARCN1B full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Zebrafish
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC.
Storage Buffer : PBS buffer
Gene Name : arcn1b archain 1b [ Danio rerio (zebrafish) ]
Official Symbol : ARCN1B
Gene ID : 399661
mRNA Refseq : NM_201993
Protein Refseq : NP_973722
UniProt ID : Q7ZU89

Related Gene

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (17)

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Can genetic variations in ARCN1B affect its function or cellular processes? 11/06/2022

Potentially, genetic variations in ARCN1B can impact its function and cellular processes. Single nucleotide polymorphisms (SNPs) or mutations in ARCN1B could lead to altered protein structure or expression levels, affecting its interactions within the COP-I complex and intracellular transport processes. However, further research is needed to determine the specific impact of such genetic variations.

Does ARCN1B have any post-translational modifications? 12/24/2021

There is limited information on the post-translational modifications of ARCN1B. However, research suggests that ARCN1B might undergo phosphorylation, which could potentially regulate its function in vesicle trafficking. Further studies are needed to fully understand the post-translational modifications of ARCN1B and their significance.

Can ARCN1B be regulated at the post-translational level? 01/26/2021

Although research specifically on ARCN1B post-translational modifications is limited, it is known that post-translational modifications can regulate the function of other COP-I complex subunits. Phosphorylation, ubiquitination, and acetylation are common post-translational modifications that can potentially influence the activity and stability of ARCN1B within the COP-I complex.

Are there any diseases associated with ARCN1B mutations or genetic variations? 11/23/2020

Limited information is available on ARCN1B mutations or genetic variations and their association with diseases. However, alterations in other components of the COP-I complex have been linked to certain disorders. Further investigation is required to determine if ARCN1B mutations contribute to disease development or progression.

Are there any known genetic disorders associated with ARCN1B mutations? 07/13/2020

The specific role and impact of ARCN1B mutations in genetic disorders are not well-established. However, mutations in other components of the COP-I complex have been linked to certain genetic disorders, including congenital disorders of glycosylation (CDGs) and skeletal dysplasias. Further research is required to determine if ARCN1B mutations contribute to any genetic disorders.

Are there any known interacting partners of ARCN1B? 07/09/2020

Yes, ARCN1B has been found to interact with various proteins involved in vesicle trafficking, such as ADP-ribosylation factor 1 (ARF1) and other subunits of the COP-I complex. These interactions are crucial for the proper assembly and function of the COP-I complex during intracellular transport.

Is there any evidence of ARCN1B involvement in cancer? 05/14/2020

Currently, there is limited research on the direct involvement of ARCN1B in cancer. However, disruptions in intracellular vesicle trafficking processes, which ARCN1B contributes to, have been implicated in cancer progression and metastasis. Further studies are needed to explore if ARCN1B dysregulation plays a role in cancer development or progression.

Can ARCN1B be targeted for therapeutic intervention? 04/06/2020

Currently, there are no known specific therapeutic interventions targeting ARCN1B. However, modulating the function of the COP-I complex, including ARCN1B, has been explored as a potential therapeutic strategy for diseases related to intracellular trafficking. Further research is needed to determine the feasibility and effectiveness of targeting ARCN1B.

What cellular processes are regulated by ARCN1B? 01/12/2020

ARCN1B primarily regulates the transport of proteins between the Golgi apparatus and the endoplasmic reticulum (ER). It plays a critical role in maintaining proper protein localization and sorting within cells.

Are there any known disease associations with ARCN1B? 01/05/2020

Currently, there are no specific disease associations reported with ARCN1B mutations or dysregulation. However, disruptions in intracellular trafficking pathways, including those involving the COP-I complex, have been implicated in various diseases, such as neurological disorders, metabolic disorders, and certain cancers. Further investigation is needed to determine if ARCN1B alterations contribute to the development or progression of any specific diseases.

Can changes in ARCN1B expression levels be associated with certain diseases? 01/03/2020

Limited information is available on the association between changes in ARCN1B expression levels and diseases. However, dysregulation of vesicle trafficking processes, in which ARCN1B is involved, has been implicated in various disorders. Further research is needed to explore if alterations in ARCN1B expression contribute to disease pathogenesis or progression.

Is ARCN1B expressed in all cell types? 05/01/2019

ARCN1B is expressed in a wide range of cell types as it plays a critical role in intracellular vesicle trafficking, which is essential for cellular functions. It is expressed in various tissues and cell lines, including epithelial cells, neurons, fibroblasts, and more.

Are there any known drugs or compounds that target ARCN1B? 08/02/2018

Currently, there are no specific drugs or compounds that directly target ARCN1B. However, targeting proteins involved in intracellular vesicle trafficking, including components of the COP-I complex, is an active area of research for developing therapies against certain diseases. Modulating ARCN1B's function indirectly through these approaches may be explored in the future.

Are there any drugs or compounds known to interact with ARCN1B? 02/02/2018

There are currently no known drugs or compounds that specifically interact with ARCN1B. However, compounds targeting other components of the COP-I complex have been investigated for their potential therapeutic applications.

What are the evolutionary conservation and homologues of ARCN1B? 04/18/2017

ARCN1B is highly conserved across various species, indicating its importance in cellular processes. Homologues of ARCN1B can be found in diverse organisms, including mammals, birds, insects, worms, and even yeast. This conservation suggests that ARCN1B's role in intracellular vesicle trafficking is evolutionary conserved and vital for cellular functions across different species.

Can ARCN1B knockout or knockdown studies provide insight into its function? 07/05/2016

Yes, knockout or knockdown studies can help elucidate the specific function and role of ARCN1B in cellular processes. By removing or reducing ARCN1B expression, researchers can observe the effects on intracellular transport, protein trafficking, and overall cell function. These studies can provide valuable insights into the importance of ARCN1B in cellular physiology.

Can ARCN1B be regulated by cellular signaling pathways? 05/10/2016

While specific signaling pathways that directly regulate ARCN1B have not been identified, it is likely that ARCN1B can be modulated by cellular signaling events. Signaling pathways that modulate protein trafficking, such as the MAPK/ERK pathway or the mTOR pathway, may indirectly affect ARCN1B function by influencing intracellular trafficking processes.

Customer Reviews (8)

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Reviews
03/19/2022

    Its superior purity and integrity make it an invaluable asset in my research endeavors.

    02/27/2022

      A manufacturer can serve as a collaborative partner, engaging in discussions, and exchanging knowledge with researchers.

      02/04/2020

        using ARCN1B protein in trials provides advantages such as its involvement in cellular processes and its disease associations.

        04/19/2019

          I am truly impressed with the capabilities of the ARCN1B Protein and highly encourage fellow researchers to incorporate it into their experimental workflows.

          01/18/2018

            This may include options like different formulations, protein modifications, or tagging techniques. Customization can enhance the versatility of the protein and optimize its utility in the intended research.

            09/03/2017

              the arfA Protein's quality and versatility make it an invaluable resource in my laboratory.

              05/24/2017

                Such support ensures researchers have access to reliable tools and expertise, facilitating their investigations into the functions, mechanisms, and disease relevance of ARCN1B protein.

                06/28/2016

                  Its consistent and reliable results have significantly enhanced the quality and accuracy of my research findings.

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