Recombinant Human Synuclein, Alpha (Non A4 Component of Amyloid Precursor), 96-140

• Cat.No.: SNCA-292H
• Product Overview: Recombinant Human α-Synuclein protein produced in E.Coli encodes 46 (96-140) amino acids and has a molecular mass of 5.2 kDa.

Specification

• Cat. No.: SNCA-292H
• Description: A deletion mutant of α-synuclein (amino acids 96-140). Syn96-140 was overexpressed in E. coli and was purified to apparent homogeneity by taking advantage of the thermosolubility of protein and by using conventional column chromatography techniques. Additional amino acid (Met) is attatched at the N-terminus.
• Source: E.coli.
• Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 0.1 M NaCl.
• Molecular Weight: 5.2 kDa (46 amino acids).
• Purity: > 95% by SDS PAGE.
• Concentration: 1 mg/ml (determined by BCA assay).
• Sequence: MKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA
• Storage: Store at -20 °C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: SNCA
• Synonyms: SNCA; synuclein, alpha (non A4 component of amyloid precursor); PD1; NACP; PARK1; PARK4; MGC110988; alpha-synuclein, isoform NACP140; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; alpha-synuclein; OTTHUMP00000161559; OTTHUMP00000161561; non A-beta component of AD amyloid; synuclein, alpha (non A4 component of amyloid precursor); Synuclein, alpha (non-Abeta component of Alzheimer"s disease amyloid precursor protein: NACP).
• Gene ID: 6622
• mRNA Refseq: NM_000345.3
• Protein Refseq: NP_000336.1
• MIM: 163890
• UniProt ID: P37840
• Chromosome Location: 4q21
• Pathway: Alzheimer"s disease; Neurodegenerative Disorders; Parkinson"s disease.
• Function: Hsp70 protein binding; alpha-tubulin binding; dynein binding; histone binding; kinesin binding; tau protein binding; transferrin transmembrane transporter activity.