Recombinant Human Synuclein, Alpha (Non A4 Component of Amyloid Precursor), 96-140

Cat. No. : SNCA-292H
Product Overview : Recombinant Human α-Synuclein protein produced in E.Coli encodes 46 (96-140) amino acids and has a molecular mass of 5.2 kDa.
Description : A deletion mutant of α-synuclein (amino acids 96-140). Syn96-140 was overexpressed in E. coli and was purified to apparent homogeneity by taking advantage of the thermosolubility of protein and by using conventional column chromatography techniques. Additional amino acid (Met) is attatched at the N-terminus.
Source : E.coli.
Formulation : Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 0.1 M NaCl.
Molecular Weight : 5.2 kDa (46 amino acids).
Purity : > 95% by SDS PAGE.
Concentration : 1 mg/ml (determined by BCA assay).
Storage : Store at -20 °C. Avoid freeze/thaw cycles.
Gene Name : SNCA
Synonyms : SNCA; synuclein, alpha (non A4 component of amyloid precursor); PD1; NACP; PARK1; PARK4; MGC110988; alpha-synuclein, isoform NACP140; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; alpha-synuclein; OTTHUMP00000161559; OTTHUMP00000161561; non A-beta component of AD amyloid; synuclein, alpha (non A4 component of amyloid precursor); Synuclein, alpha (non-Abeta component of Alzheimer"s disease amyloid precursor protein: NACP).
Gene ID : 6622
mRNA Refseq : NM_000345.3
Protein Refseq : NP_000336.1
MIM : 163890
UniProt ID : P37840
Chromosome Location : 4q21
Pathway : Alzheimer"s disease; Neurodegenerative Disorders; Parkinson"s disease.
Function : Hsp70 protein binding; alpha-tubulin binding; dynein binding; histone binding; kinesin binding; tau protein binding; transferrin transmembrane transporter activity.

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