Active Recombinant Human IL6

• Cat.No.: IL6-1H
• Product Overview: Human Interleukin-6 (RECOMBINANT) is produced in genetically engineered Spodoptera frugiperda insect cells (Sf9) infected with recombinant viruses, and purified by sequential chromatography.

Specification

• Description: Human Interleukin-6 (IL-6) plays a role in the mediation of the inflammatory and immune response initiated by infection or injury. IL-6 acts on B cells by stimulating differentiation and antibody secretion. IL-6 also exhibits growth factor activity for mature thymic or peripheral T cells, and enhances the differentiation of cytotoxic T cells in the presence of IL-2 or IFNt. This glycoprotein is composed of 184 amino acid residues, and has a 42% homology with murine IL-6.
• Source: Sf9 cells
• Species: Human
• Form: Frozen liquid solution (PBS) at 0.50 mg/ml (50 μl/vial)
• Bio-activity: 3H-thymidine uptake by B9 murine thymoma cell line that is IL-6 dependent.
• Molecular Mass: 20-21 KDa (glycoprotein)
• Purity: Over 85% pure by SDS gel electrophoresis. There is< 1ng/mg>
• Stability: At least 1 year at -80°C.
• Storage: Store at -80°C.

Gene Information

• Gene Name: IL6 interleukin 6 [ Homo sapiens (human) ]
• Official Symbol: IL6
• Synonyms: HGF; BSF2; HSF; IFNB2; IL-6; CDF; BSF-2; B-cell stimulatory factor 2; CTL differentiation factor; Hybridoma growth factor; Interferon beta-2; Interleukin-6 precursor; interleukin 6 (interferon, beta 2); IL6
• Gene ID: 3569
• mRNA Refseq: NM_000600
• Protein Refseq: NP_000591
• MIM: 147620
• UniProt ID: P05231
• Chromosome Location: 7p21
• Pathway: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Prion disease, Toll-like receptor signaling pathway
• Function: Cytokine activity, Interleukin-6 receptor binding, Protein binding