Active Recombinant Human Acidic Fibroblast Growth Factor
Cat.No. : | FGF1-4H |
Product Overview : | Human Acidic FGF is produced by genetically engineered yeast, and purified by heparin-Sepharose affinity chromatography. |
- Specification
- Gene Information
- Related Products
Description : | Acidic FGF is a mitogen for cells of mesodermal and neuroectodermal origin, including fibroblasts, endothelial cells, astrocytes, neuroblasts, osteoblasts, and smooth muscle cells. This protein is composed of 140 amino acid residues, and has a 55% homology with basic FGF, including two conserved cysteine residues.? |
Source : | yeast |
Species : | Human |
Form : | 10 mM Tris-HCl, 1.5 M NaCl, pH 7.0 Concentration: 0.50 mg protein/ml. |
Bio-activity : | Human acidic FGF is mitogenic for a variety of normal cells in culture including fibroblasts, glial cells, vascular endothelial cells. |
Molecular Mass : | 15.5 KDa |
Purity : | Over 95% pure by HPLC analysis and SDS gel electrophoresis. |
Stability : | Unstable without a carrier protein like gelatin or bovine serum albumin. It is recommended to add some of these proteins, prior to aliquoting, for longer storage. |
Storage : | Store at -80°C. It is also possible to keep this protein at low pH (2-5) for a few days. |
Gene Name : | FGF1 fibroblast growth factor 1 (acidic) [ Homo sapiens (human) ] |
Official Symbol : | FGF1 |
Synonyms : | FGF1; fibroblast growth factor 1 (acidic); AFGF; ECGF; FGFA; ECGFA; ECGFB; HBGF1; GLIO703; FGF-alpha; ECGF-beta; Acidic fibroblast growth factor; OTTHUMP00000066031; heparin-binding growth factor 1; endothelial cell growth factor, beta; endothelial cell growth factor, alpha; Beta-endothelial cell growth factor; OTTHUMP00000066028; OTTHUMP00000174675; OTTHUMP00000066030 |
Gene ID : | 2246 |
mRNA Refseq : | NM_000800 |
Protein Refseq : | NP_000791 |
MIM : | 131220 |
UniProt ID : | P05230 |
Chromosome Location : | 5q31 |
Pathway : | MAPK signaling pathway; Melanoma; Pathways in cancer; Regulation of actin cytoskeleton |
Function : | growth factor activity; heparin binding; protein binding |
Products Types
◆ Recombinant Protein | ||
FGF1-1514R | Recombinant Rhesus Macaque FGF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FGF1-77H | Active Recombinant Human FGF1 Protein | +Inquiry |
FGF1-78M | Recombinant Mouse/Rat FGF1 Protein | +Inquiry |
FGF1-1980R | Recombinant Rat FGF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Fgf1-057M | Active Recombinant Mouse Fgf1 Protein | +Inquiry |
◆ Native Protein | ||
FGF1-26203TH | Native Human FGF1 | +Inquiry |
FGF1-33B | Active Native Bovine FGF1 | +Inquiry |
◆ Lysates | ||
FGF1-6252HCL | Recombinant Human FGF1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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