Active Recombinant Human CXCL2

• Cat.No.: CXCL2-17H
• Product Overview: Human recombinant MIP-2 alpha is produced in genetically engineered yeast, and purified by sequential chromatography.

Specification

• Description: This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation.
• Source: yeast
• Species: Human
• Form: In 20 mM HEPES/0.1 M NaCl (ph7.3) at a concentration of 1.0 mg protein/
• Bio-activity: The biological activity of recombinant human MIP-2 alpha is determined by its use as a cofactor for CSF-dependent myelopoiesis.
• Purity: Over 95% pure by SDS gel electrophoresis, with low level of endotoxin.
• Stability: Several months at -80°C.
• Storage: Store at -80°C.

Gene Information

• Gene Name: CXCL2 chemokine (C-X-C motif) ligand 2 [ Homo sapiens (human) ]
• Official Symbol: CXCL2
• Synonyms: CXCL2; GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a; MIP2-alpha; MIP-2a; Gro-beta; C-X-C motif chemokine 2; GRO2 oncogene; Growth-regulated protein beta; MGSA beta; chemokine (C-X-C motif) ligand 2; melanoma growth stimulatory activity beta; MIP2A_HUMAN; Macrophage inflammatory protein 2-alpha [Precursor]; Gro-beta
• Gene ID: 2920
• mRNA Refseq: NM_002089
• Protein Refseq: NP_002080
• MIM: 139110
• UniProt ID: P19875
• Chromosome Location: 4q21
• Pathway: Chemokine receptors bind chemokines; Chemokine signaling pathway; G alpha (i) signalling events
• Function: CXCR chemokine receptor binding; chemokine activity; protein binding