Active Recombinant Human Caspase-9 Enzyme

• Cat.No.: CASP9-34H

Specification

• Species: Human
• Form: Lyophilized powder.
• Bio-activity: 400 units/mg.
• Purity: ≥90% by SDS-PAGE
• Unit Definition: One unit is the enzyme activity that cleaves 1 nmol of the caspase substrate LEHD-pNA per hour at 37°C in a reaction solution containing 50 mM Hepes, pH 7.2, 50 mM NaCl, 0.1% Chaps, 10 mM EDTA, 5% Glycerol, and 10 mM DTT.
• Usage: For in vitro research use only. Not for use in diagnostics or in humans.
• Storage: Stable at -80°C for 1 year. Following reconstitution in PBS, the enzyme should be aliquoted and immediately stored at -80°C. Avoid multiple freeze/thaw cycles as activity might decrease.
• Warning: No warranties, expressed or implied, are made regarding the use of this product. Creative Biomart is not liable for any damage, personal injury, or economic loss caused by this product.

Gene Information

• Gene Name: CASP9 caspase 9, apoptosis-related cysteine peptidase [ Homo sapiens ]
• Official Symbol: CASP9
• Synonyms: CASP9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis related cysteine protease; caspase-9; APAF 3; ICE LAP6; MCH6; PPP1R56; protein phosphatase 1; regulatory subunit 56; apoptotic protease MCH-6; ICE-like apoptotic protease 6; apoptotic protease activating factor 3; protein phosphatase 1, regulatory subunit 56; APAF3; APAF-3; ICE-LAP6; CASPASE-9c
• Gene ID: 842
• mRNA Refseq: NM_001229
• Protein Refseq: NP_001220
• MIM: 602234
• UniProt ID: P55211
• Chromosome Location: 1p36.21
• Pathway: AKT phosphorylates targets in the cytosol, organism-specific biosystem; Activation of caspases through apoptosome-mediated cleavage, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem
• Function: cysteine-type endopeptidase activity; enzyme activator activity; peptidase activity; protein binding