Recombinant Human TRAIL-R3, Fc-tagged

• Cat.No.: TNFRSF10C-68H
• Product Overview: The extracellular domain (amino acids 25-240) of human TRAIL-R3 fused to the Fc portion of human IgG1.

Specification

• Species: Human
• Tag: Fc
• Form: 50 μg lyophilized, purified protein. Dissolve in 50 μL sterile H2O to obtain a 1 mg/mL solution in PBS.
• Molecular Mass: ~66 kDa (SDS-PAGE).
• Purity: >95% as determined by SDS-PAGE
• Characteristic: Interacts with TRAIL from human and mouse. Other species not tested.
• Usage: For in vitro research use only. Not for use in diagnostics or in humans.
• Storage: Unreconstituted product is stable at -20°C for a minimum of 6 months. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
• Warning: No warranties, expressed or implied, are made regarding the use of this product. Creative Biomart is not liable for any damage, personal injury, or economic loss caused by this product.

Gene Information

• Gene Name: TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain [ Homo sapiens ]
• Official Symbol: TNFRSF10C
• Synonyms: TNFRSF10C; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain; tumor necrosis factor receptor superfamily member 10C; CD263; DcR1; LIT; TRAILR3; TRID; decoy receptor 1; cytotoxic TRAIL receptor-3; lymphocyte inhibitor of TRAIL; decoy TRAIL receptor without death domain; antagonist decoy receptor for TRAIL/Apo-2L; TNF-related apoptosis-inducing ligand receptor 3; DCR1; TRAIL-R3; DCR1-TNFR; MGC149501; MGC149502
• Gene ID: 8794
• mRNA Refseq: NM_003841
• Protein Refseq: NP_003832
• MIM: 603613
• UniProt ID: O14798
• Chromosome Location: 8p22-p21
• Pathway: Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Direct p53 effectors, organism-specific biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem
• Function: TRAIL binding; binding; receptor activity; transmembrane signaling receptor activity