Recombinant Human VDAC1, GST-tagged

• Cat.No.: VDAC1-18H
• Product Overview: Recombinant Human VDAC1, fused with N-terminal GST, was expressed in E. coli.

Specification

• Description: This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: 1M PBS (58 mM Na2HPO4, 17 mM NaH2PO4, 68 mM NaCl, pH8.0 ), 100 mM GSH and 1% Triton X-100, 15% glycerol.
• Bio-activity: Not tested
• AA Sequence: MAVPPTYADLGKSARDVFTKGYGFG LIKLDLKTKSENGLEFTSSGSANTE TTKVTGSLETKYRWTEYGLTFTEKW NTDNTLGTEITVEDQLARGLKLTFD SSFSPNTGKKNAKIKTGYKREHINL GCDMDFDIAGPSIRGALVLGYEGWL AGYQMNFETAKSRVTQSNFAVGYKT DEFQLHTNVNDGTEFGGSIYQKVNK KLETAVNLAWTAGNSNTRFGIAAKY QIDPDACFSAKVNNSSLIGLGYTQT LKPGIKLTLSALLDGKNVNAGGHKL GLGLEFQA(1-283aa encoded by BC008482)
• Endotoxin: Please contact the lab for more information.
• Stability: Aliquot and store at -20°C to -80°C for up to 6 months. Avoid freeze thaw cycles.
• Shipping: The product is shipped with ice packs. Upon receipt, store it immediately at -20°C to -80°C.

Gene Information

• Gene Name: VDAC1 voltage-dependent anion channel 1 [ Homo sapiens (human) ]
• Official Symbol: VDAC1
• Synonyms: VDAC1; voltage-dependent anion channel 1; PORIN; VDAC-1; voltage-dependent anion-selective channel protein 1; porin 31HL; porin 31HM; plasmalemmal porin; outer mitochondrial membrane protein porin 1
• Gene ID: 7416
• mRNA Refseq: NM_003374
• Protein Refseq: NP_003365
• MIM: 604492
• UniProt ID: P21796
• Chromosome Location: 5q31
• Pathway: Calcium signaling pathway; HTLV-I infection; Huntington's disease; Metabolism of proteins
• Function: porin activity; protein kinase binding; voltage-gated anion channel activity