Description : |
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008] |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
69.4 kDa |
AA Sequence : |
MPKPINVRVTTMDAELEFAIQPNTT GKQLFDQVVKTIGLREVWYFGLHYV DNKGFPTWLKLDKKVSAQEVRKENP LQFKFRAKFYPEDVAEELIQDITQK LFFLQVKEGILSDEIYCPPETAVLL GSYAVQAKFGDYNKEVHKSGYLSSE RLIPQRVMDQHKLTRDQWEDRIQVW HAEHRGMLKDNAMLEYLKIAQDLEM YGINYFEIKNKKGTDLWLGVDALGL NIYEKDDKLTPKIGFPWSEIRNISF NDKKFVIKPIDKKAPDFVFYAPRLR INKRILQLCMGNHELYMRRRKPDTI EVQQMKAQAREEKHQKQLERQQLET EKKRRETVEREKEQMMREKEELMLR LQDYEEKTKKAERELSEQIQRALQL EEERKRAQEEAERLEADRMAALRAK EELERQAVDQIKSQEQLAAELAEYT AKIALLEEARRRKEDEVEEWQHRAK EAQDDLVKTKEELHLVMTAPPPPPP PVYEPVSYHVQESLQDEGAEPTGYS AELSSEGIRDDRNEEKRITEAEKNE RVQRQLLTLSSELSQARDENKRTHN DIIHNENMRQGRDKYKTLRQIRQGN TKQRIDEFEALTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |